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  #1  
Old 09-24-2010
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Question Peutz-Jeghers

Is Peutz-Jeghers a risk for colorectal cancer??????
FA Says yes. Kaplan and Goljan say NO.
Which one is correct?????
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Old 09-24-2010
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Almost 50% of patients with Peutz-Jeghers syndrome (PJS) develop and die from cancer by age 57 years. The mean age at first diagnosis of cancer is 42.9 years, +/ 10.2 years

Source : http://emedicine.medscape.com/article/182006-overview
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Old 09-24-2010
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Quote:
Originally Posted by donofitaly View Post
Almost 50% of patients with Peutz-Jeghers syndrome (PJS) develop and die from cancer by age 57 years. The mean age at first diagnosis of cancer is 42.9 years, +/ 10.2 years

Source : http://emedicine.medscape.com/article/182006-overview
Yes absolutelly, in addition to developing cancer in other sites like esophagus, breast, lungs, they are at increased risk of develping colon cancer.
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Old 09-25-2010
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well Peutz-Jeghers is asso. with the risk of colorectal cancer....but its not from polyp..they are mere hamartomas...polyps are present only in stomach n small intestine in Peutz-Jeghers..not in sigmoid colon....

there is high incidence of colorectal cancer n certain sex cord tumors in Peutz-Jeghers......
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Gastrointestinal-Tract-, Syndromes-Acronyms

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