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Old 03-18-2013
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Drug Thiazide diuretics and Uric Acid Secretion!

how does thiazide cause decrease in excretion of uric acid?
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Old 03-18-2013
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While u guys at it, can u tell why thiazide causes hyperlipidemia?
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Old 03-20-2013
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Quote:
Originally Posted by bigBOSSguy View Post
While u guys at it, can u tell why thiazide causes hyperlipidemia?
read on couple of sites.. this kinda sums it up.. and it made sense to me:

Answer:
Diuretics (For e.g. Thiazide) causes Hypokalemia. It will cause the potassium to be secreted in urine. Due to hypokalemia, there will be less insulin release (as both depend on each other). The less amount of insulin release cause the glucose level to rise in plasma, causing Hyperglycemia. As the glucose level rises, there will be more Triglycerides form, it will lead to LDL(low density lipoproteins) and Very Low Density Liporoteins- These are bad cholestrol-Causing Hyperlipidemia.
Hope it helps.

-Shua

http://wiki.answers.com/Q/How_do_diu...hyperlipidemia

this is a useful thread too
Diuretics Rules & Exceptions
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The above post was thanked by:
ehtisham (03-20-2013), Ramla (06-17-2014)



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Pharmacology-, Physiology-, Renal-

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