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Old 03-26-2013
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Drug 6 mercaptopurin mechanism of action

in dit.. they said that 6MP inhibits PRPP synthatase.. while i'm following with them i found my notes say (and wikipedia too) said 6 MP inhibits PRPP amidotransferase..
does it inhibit both? or which one is correct
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PRPP amidotransferase
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Old 03-27-2013
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Ribose 5 Po4--prpp synthetase-- PRPP---amidotransferase---5 phosphoribosyl amine---IMP---- AMP and GMP..

6 MP inhibits Amidotransferase . Kaplan...
( Yes, i too was confused due to dit lecture).
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