Pulmonary Vascular Vasoconstrictor the cause of Systemic Hypertension? - USMLE Forums
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Old 04-19-2013
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Vascular Pulmonary Vascular Vasoconstrictor the cause of Systemic Hypertension?

) A 41 year old woman comes to the physician for a follow up examination 6 weeks after the diagnosis of hypertension was made. Her blood pressure today is 162/ 104 mm hg. A right abdominal bruit is heard. Physical examination shows no other abnormalities . Serum studies show :
na+ 135
k+ 3.2
cl- 105
hco3 28
urea nitrogen 9
creatine 0.9

on renal arteriography, sampling shows a left renal vein activity of 5 mu/ml( n 5-97) and renal vein renin activity of 176 mu/ml ( N 9-97). the systemic hypertension in the patient is directly mediated by a vasoconstrictor that emerges from which of the following ?

a- adrenal medullary chromafin cells
b- glomerular afferent arteriole
c- glomerular efferent arteriole
d- pulmonary vasculature
e- renal juxtaglomerular cells


The answer was D , but i dont understand why anyone please?
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Old 04-19-2013
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ACE is present abundantly in the pulmonary vasculature, and it converts Angiotensin I to the physiologically active Angiotensin II
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