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  #1  
Old 04-20-2013
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Bacteria Bacterial Genetics Terms!

Can someone please explain to me in very very basic terms what the following 4 terms mean. I have included a very basic definition for some:

1. Recombination- Only happens in segmented viruses?
2. Resortment- only happens in Influenza virus? Whole genomes get exchanged?
3. Complementation
4. Phenotype mixing

I have read First Aid and the Uworld explanations but find it rather difficult and tend to get these answers wrong.

Thanks for your help
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Old 04-22-2013
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Recombination:
Recombination in other words in genetic shift. A person sitting in a Bus A, swaps his seat with an almost exactly similar Bus B with a better seat standing right next to it. So they just slide the seat between each other.
The change in genetic make up is small, enough to evade our normal treatment/prevention measure but usually not big enough to be uncontrollable.
Genetic Shift/Recombination has potential to cause epidemics(evasion from our most common/routine responses).

Re-assortment:
Reassortment is genetic drift between similar genetic makeups. it's an outright change of material with/from another species with a close-looking genetic makeup. Think of this as swapping a seat from one bus with another person sitting in the subway. Has the ability to cause pandemics because of it's potential to have previously unknown, unrelated product.

Complementation:
When one lacks something the other close-by has. When the two meet they make a good team by helping the other one out by giving him what he doesn't have.

Phenotypic Mixing:
Related viruses having a capsid(The outwordly appearance-the phenotype) a mixture of each other. Virus A and Virus B mix producing a Virus A Nucleic Acid core with a capsid of A+B proteins mixture and Virus B genetic material covered by a capsid made up of A+B.

Last edited by Insomniac; 04-22-2013 at 01:43 AM. Reason: Clarity
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Old 04-22-2013
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Quote:
Originally Posted by Insomniac View Post
Recombination:
Recombination in other words in genetic shift. A person sitting in a Bus A, swaps his seat with an almost exactly similar Bus B with a better seat standing right next to it. So they just slide the seat between each other.
The change in genetic make up is small, enough to evade our normal treatment/prevention measure but usually not big enough to be uncontrollable.
Genetic Shift/Recombination has potential to cause epidemics(evasion from our most common/routine responses).

Re-assortment:
Reassortment is genetic drift between similar genetic makeups. it's an outright change of material with/from another species with a close-looking genetic makeup. Think of this as swapping a seat from one bus with another person sitting in the subway. Has the ability to cause pandemics because of it's potential to have previously unknown, unrelated product.

Complementation:
When one lacks something the other close-by has. When the two meet they make a good team by helping the other one out by giving him what he doesn't have.

Phenotypic Mixing:
Related viruses having a capsid(The outwordly appearance-the phenotype) a mixture of each other. Virus A and Virus B mix producing a Virus A Nucleic Acid core with a capsid of A+B proteins mixture and Virus B genetic material covered by a capsid made up of A+B.
hey thanks for the simplified explanation..but correct me if im wrong...isnt genetic shift causing reassortment in influenza and rota virus because of their segmented genome? i think genetic drift is in recombination and shift in reassortment.
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Old 04-22-2013
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Can RE-ASSORTMENT happen with any segmented virus?


Thanks for the simplified explanation
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Old 04-22-2013
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Quote:
Originally Posted by OMGStep View Post
Can RE-ASSORTMENT happen with any segmented virus?


Thanks for the simplified explanation
the classic example is orthomyxoviruses
but possibility for other segmented viruses exists
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