Diuretics - Mechanisms - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 10-14-2010
USMLE Forums Guru
 
Steps History: 1 + CS
Posts: 405
Threads: 55
Thanked 528 Times in 155 Posts
Reputation: 538
Drug Diuretics - Mechanisms

Hello to all fellow members,

I am studying the Diuretics pharmacology, explained excellently by Dr.Lionel Raymon. Its so refreshing to see how he is explaining not only the mechanism of the action of the drug but also how the side effects can be understood so well.

However, i am wondering if we should know the mechanism of side effects as well? I mean even though its easy to say yeah now i know the mechanism, it will be rather difficult to remember it for a long time and not to get confused. Will it suffice if i stick up a table with drugs, their MOA and Side effects and just learn them accordingly? Will this help me with the questions in the exams?
Reply With Quote Quick reply to this message
The above post was thanked by:
cuteguy (10-15-2010)



  #2  
Old 10-14-2010
Haisook's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 752
Threads: 124
Thanked 614 Times in 265 Posts
Reputation: 634
Default

Well, most of the time, it's enough to know where each diuretic act, and what SEs they have. But you can't trust the examiner! May be he/she is in the mood for asking why acetazolamide causes hyperchloremic metabolic acidosis? Or why spironolactone can cause gynecomastia?

So try to know everything if you have the time. I actually find the 3-page section of FA on diuretics to be enough. I think it says everything, mostly. So do the Kaplan notes with Dr Raymon once, and move on to FA.
Reply With Quote Quick reply to this message
The above post was thanked by:
cuteguy (10-15-2010), donofitaly (10-15-2010), rasheed (10-14-2010)
  #3  
Old 10-14-2010
USMLE Forums Newbie
 
Steps History: 1+CK+CS+3
Posts: 2
Threads: 0
Thanked 2 Times in 2 Posts
Reputation: 12
Default

hello, my friend , has just passed step 1 , and he recommend koljan pharmacology becuz it's more detailed , and he always says :stay in the green zone. so if u have time , i suggest a more detailed notes.
Reply With Quote Quick reply to this message
The above post was thanked by:
donofitaly (10-15-2010)
 
  #4  
Old 10-15-2010
USMLE Forums Guru
 
Steps History: 1 + CS
Posts: 405
Threads: 55
Thanked 528 Times in 155 Posts
Reputation: 538
Smile

Thanks a lot for your responses.

And yes Haisook, if they are going to frame questions your style, i better study everything very well. Love your questions brother!
Reply With Quote Quick reply to this message
  #5  
Old 10-15-2010
dazzles's Avatar
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 137
Threads: 24
Thanked 112 Times in 37 Posts
Reputation: 122
Default

Is the mechanism of gynecomastia with Spironolactone just that it's an antiandrogen or is it more complicated than that?
Reply With Quote Quick reply to this message
  #6  
Old 10-16-2010
USMLE Forums Guru
 
Steps History: 1 + CS
Posts: 405
Threads: 55
Thanked 528 Times in 155 Posts
Reputation: 538
Smile

Quote:
Originally Posted by dazzles View Post
Is the mechanism of gynecomastia with Spironolactone just that it's an antiandrogen or is it more complicated than that?
From what i understood from the lectures, its a non-selective steroidal drug hence its antiandrogenic activity.
Reply With Quote Quick reply to this message
  #7  
Old 10-16-2010
dazzles's Avatar
USMLE Forums Addict
 
Steps History: 1+CK+CS
Posts: 137
Threads: 24
Thanked 112 Times in 37 Posts
Reputation: 122
Default

Thanks. I found the answer. Spironolactone inhibits steroid (testosterone) from binding to it's receptor. That's also why it can be used in PCOS to help with hirsutism. Women with PCOS have increased testosterone because of theca cell hyperplasia from increased LH. It's pg. 495 - 496 FA. I think I need to read FA more carefully!
Reply With Quote Quick reply to this message
The above post was thanked by:
donofitaly (10-16-2010)
  #8  
Old 10-16-2010
Haisook's Avatar
USMLE Forums Master
 
Steps History: 1+CK+CS+3
Posts: 752
Threads: 124
Thanked 614 Times in 265 Posts
Reputation: 634
Default

Quote:
Originally Posted by donofitaly View Post
And yes Haisook, if they are going to frame questions your style, i better study everything very well. Love your questions brother!
Thanks. Although I have fun writing the questions, I wouldn't want to see a lot of such ones in the exam! Standing behind gunfire is way different from standing in front of it!
Reply With Quote Quick reply to this message



Reply

Tags
Pharmacology-

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Husban & Wife in Mental Defense Mechanisms; Some interesting examples Sabio USMLE Step 1 Bits & Pieces 11 02-09-2011 06:48 PM
Diuretics Rules & Exceptions rasheed USMLE Step 1 Bits & Pieces 1 03-09-2010 10:14 AM
Quick revision of diuretics-Animation docspike USMLE Step 1 Forum 2 10-20-2009 02:18 AM
I want to skip Mental Defense Mechanisms causca USMLE Step 1 Forum 1 07-11-2009 11:40 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)