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USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


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  #1  
Old 05-30-2013
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Group talk August 2013 Step 1 Takers

hi everyone,
Whose taking the step1 in august.... only 3 months and i'm in serious need of support and motivation... let's discuss our study plans and questions and anything...
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  #2  
Old 05-30-2013
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also has anyone tried booking a seat in prometric? There seems to be only hyderabad available.... is something wrong with bangalore and all?? or are the already full??
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Old 05-30-2013
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oh oh and... first aid for usmle step 1 is available in torrent.... get it soon... this is 2013 one...
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  #4  
Old 06-02-2013
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Quote:
Originally Posted by vinaya View Post
oh oh and... first aid for usmle step 1 is available in torrent.... get it soon... this is 2013 one...
I'm planning to take the exam in september as well. But so far I haven't even finished one read of Kaplan!
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  #5  
Old 06-02-2013
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Hi Guys!

I am planning to take the test during the second week of August. So far I am done with 2 reads of Kaplan + a very quick third read (left with Pharma my weak link) + one read of first aid + Kaplan Q bank offline.
Now I plan to finish Pharma then hop on to FA for the second time + FA Q & A and hopefully start UWORLD on the 20th.

Nice thread we should keep ourselves motivated just a matter of 2 months now and hopefully we will all ACE it!
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  #6  
Old 06-02-2013
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Quote:
Originally Posted by Dr.Sidd View Post
Hi Guys!

I am planning to take the test during the second week of August. So far I am done with 2 reads of Kaplan + a very quick third read (left with Pharma my weak link) + one read of first aid + Kaplan Q bank offline.
Now I plan to finish Pharma then hop on to FA for the second time + FA Q & A and hopefully start UWORLD on the 20th.

Nice thread we should keep ourselves motivated just a matter of 2 months now and hopefully we will all ACE it!

That sounds super scary to me. I'm hardly done even a third of what you have.
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  #7  
Old 06-03-2013
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Originally Posted by jean View Post
That sounds super scary to me. I'm hardly done even a third of what you have.
Don't worry I am the type who needs frequent repetitions and have always been an average student without a good knowledge base hence the extra time and effort. You will be fine!
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  #8  
Old 06-03-2013
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Hi, How are you all and how is your cortisol level until now

I have been waiting for August exam takers thread

I'm going over FA now along with kaplan videos and other resources, trying to do questions more often, but the time eats me up alive and I've been having a hard time keeping up to my scheduled subjects.


mmmm ,I have a question

How many questions do you do each day ?
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  #9  
Old 06-03-2013
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Quote:
Originally Posted by Dr.Sidd View Post
Hi Guys!

I am planning to take the test during the second week of August. So far I am done with 2 reads of Kaplan + a very quick third read (left with Pharma my weak link) + one read of first aid + Kaplan Q bank offline.
Now I plan to finish Pharma then hop on to FA for the second time + FA Q & A and hopefully start UWORLD on the 20th.

Nice thread we should keep ourselves motivated just a matter of 2 months now and hopefully we will all ACE it!
Wow... that's a lot you have read!!! well i'm in my second read doing this and uworld.... going slow... but fairly steady i guess... pharma is my weak link too!! of course and path too.... so many drugs and side effects... ... reading that now... how is yours??
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Old 06-03-2013
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Quote:
Originally Posted by Dr. Egocentric View Post
Hi, How are you all and how is your cortisol level until now

I have been waiting for August exam takers thread

I'm going over FA now along with kaplan videos and other resources, trying to do questions more often, but the time eats me up alive and I've been having a hard time keeping up to my scheduled subjects.


mmmm ,I have a question

How many questions do you do each day ?
hey... well i manage around 60-70... i do 2 sessions of 35 each... have to increase to 46 slowly....
time is a problem for me too... get so distracted!! but they say qs are the key... though sometimes the explanations are so long... it takes me 2 day sto complete the 70 qs....
does this happen to everyone??
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  #11  
Old 06-03-2013
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Quote:
Originally Posted by vinaya View Post
Wow... that's a lot you have read!!! well i'm in my second read doing this and uworld.... going slow... but fairly steady i guess... pharma is my weak link too!! of course and path too.... so many drugs and side effects... ... reading that now... how is yours??
I'm yet to start fa or uworld. I'll be completing my first read only this month. how would you suggest I go bout my schedule now?
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  #12  
Old 06-03-2013
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Quote:
Originally Posted by Dr.Sidd View Post
Hi Guys!

I am planning to take the test during the second week of August. So far I am done with 2 reads of Kaplan + a very quick third read (left with Pharma my weak link) + one read of first aid + Kaplan Q bank offline.
Now I plan to finish Pharma then hop on to FA for the second time + FA Q & A and hopefully start UWORLD on the 20th.

Nice thread we should keep ourselves motivated just a matter of 2 months now and hopefully we will all ACE it!
yeah!! motivation is the key.... i keep telling myself just a few more months and this will be over...

Sooo.... I think we should discuss qs and topics here... like put up hints and mnemonics that help us remember...I'll write down whatever I come up with....
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Old 06-03-2013
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Quote:
Originally Posted by jean View Post
I'm yet to start fa or uworld. I'll be completing my first read only this month. how would you suggest I go bout my schedule now?
Well personally i take FA as a revision and memorizing tool, so I finished my first read before I started that... you still have time... second reads are easier... you remember more... and FA helps remember.. it consolidates all the points together....
apart from that .... Uworld i guess you should start as soon as possible... I started long back.... coz i felt qs help me decide how i should read the books.... like in pharma I was reading today... Vancomycin is a back up drug for c.diff.... and a qs can be asked as the drug to give for C.diff infection under situations where metronidazole can't be used.... By reading qs you know how to approach a subject....
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  #14  
Old 06-03-2013
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Hey guys planning on taking step 1 in Aug but had to reapply... So waiting for the permit to come through soon. Im done with my second read of kaplan except for biochem and pharma. Will do FA and UWORLD after that...
Good thread guys keep it going.
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Old 06-03-2013
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Quote:
Originally Posted by vinaya View Post
Wow... that's a lot you have read!!! well i'm in my second read doing this and uworld.... going slow... but fairly steady i guess... pharma is my weak link too!! of course and path too.... so many drugs and side effects... ... reading that now... how is yours??
My first read was basically a makeup for the lost time in medical school, which is not the case with everyone. So don't get overwhelmed by how much I have read so far.

I don't know if its realistic but I am targeting a 250+ despite all odds. Lets see how UWorld goes since I won't be using it just as a learning tool but as an evaluation tool as well.

The mistake which I made so far was not doing Kaplan Qbank in a random and timed mode. So I will do FA Q and A which has the last few blocks in a mixed random format of 7 blocks before starting Uworld. Will not repeat the same mistakw with UWorls this time.
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  #16  
Old 06-03-2013
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Quote:
Originally Posted by Dr.Sidd View Post
My first read was basically a makeup for the lost time in medical school, which is not the case with everyone. So don't get overwhelmed by how much I have read so far.

I don't know if its realistic but I am targeting a 250+ despite all odds. Lets see how UWorld goes since I won't be using it just as a learning tool but as an evaluation tool as well.

The mistake which I made so far was not doing Kaplan Qbank in a random and timed mode. So I will do FA Q and A which has the last few blocks in a mixed random format of 7 blocks before starting Uworld. Will not repeat the same mistakw with UWorls this time.
250 is a realistic goal and given the consistency you've maintained in studying, you should be able to do it. I know people who have.
Besides I've been told that being img we must aim only for nothing less than 250.
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  #17  
Old 06-03-2013
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Hi guys!!

I am planning to take my test in last week of august.So far,i finished 2 reading from kaplan, 2 read from FA.I did kaplan qbank along with my second read from in a subject wise manner.i started Uworld 1week back and 30% finished.

Nice thread to keep ourselves motivated and to solve any kind of confusion
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Old 06-03-2013
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Quote:
Originally Posted by vinaya View Post
hey... well i manage around 60-70... i do 2 sessions of 35 each... have to increase to 46 slowly....
time is a problem for me too... get so distracted!! but they say qs are the key... though sometimes the explanations are so long... it takes me 2 day sto complete the 70 qs....
does this happen to everyone??

Today its the first time for me to do a 46 questions in a row, simulating the real exam block. I only did it for anatomy, histology and embryology so questions didn't require a lot of time for me to understand it.

I think if I did it in Pharm it would be a lot harder and challenging,

for that reason I think of taking specific days from my schedule and giving my self a time to simulate the real deal with 322 questions in 7 blocks and 46 Q each


I know reviewing that will take a tremendous amount of time, but I want to increase my endurance, fast response and correct answers in tough subjects like pharm or phys


So what do you think of that ?
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Old 06-03-2013
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I have a similar plan for doing uworld. I am dividing it into 7 test days of random timed 7 blocks. On the test day I will revise one block and the following two days I will revise 3 blocks each day. I will annotate my first aid along. I am using this method to monitor my progress in an exam simulated manner to see if I'm improving from one test day to another.
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Old 06-03-2013
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ok I have a good qs....
1 yr old boy brought to emergency dept by mother for high fever, irritability and photophobia. he has undergone ventriculoperitoneal shunt placement for hydrocephalus.
T- 101f
Flexion of neck- spontaneous flexion of hips and knees
Blood culture- COAGULASE -VE STAPH
What is the most imp virulence mech to cause disease?
1) intracellular existence
2)outer polysac capsule
3)presence of protein A
4)release of exotoxin
5)syn of extracellular polysacc matrix
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  #21  
Old 06-03-2013
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Quote:
Originally Posted by Dr. Egocentric View Post
Today its the first time for me to do a 46 questions in a row, simulating the real exam block. I only did it for anatomy, histology and embryology so questions didn't require a lot of time for me to understand it.

I think if I did it in Pharm it would be a lot harder and challenging,

for that reason I think of taking specific days from my schedule and giving my self a time to simulate the real deal with 322 questions in 7 blocks and 46 Q each


I know reviewing that will take a tremendous amount of time, but I want to increase my endurance, fast response and correct answers in tough subjects like pharm or phys


So what do you think of that ?
That is a great idea.... With only 2 months left... that would be a good ...
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  #22  
Old 06-03-2013
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Quote:
Originally Posted by Dr.Sidd View Post
My first read was basically a makeup for the lost time in medical school, which is not the case with everyone. So don't get overwhelmed by how much I have read so far.

I don't know if its realistic but I am targeting a 250+ despite all odds. Lets see how UWorld goes since I won't be using it just as a learning tool but as an evaluation tool as well.

The mistake which I made so far was not doing Kaplan Qbank in a random and timed mode. So I will do FA Q and A which has the last few blocks in a mixed random format of 7 blocks before starting Uworld. Will not repeat the same mistakw with UWorls this time.
Hi 250 is a great goal..... Seems realistic to me... since a lot of people have been able to achieve it.... My dad would say.. aim for 110%... then inspite of your carelessness and stupidity and all you should land at 100... So i'm aiming for 260s!!!

What is everyone else aiming for?? DO you know anyone who achieved above 250 and all... what advice do they give??
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  #23  
Old 06-03-2013
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E. is the answer. Its the biofilm that helps it to bind to the shunt. Read a similar question in kaplan
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Old 06-04-2013
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hi... looks like everyone had a lazy afternoon like me

Well the answer to that qs is definitely e) ....

The reason is because of their ability to form biofilms...

when foreign bodies enter the body, they are coated by host proteins- fibronectin and fibrinogen. they provide binding site for bacteria like staph. epi-
Once they bind they communicate with other bacteria and induce synthesis of extracellular polysacc matrix that encase bacteria.These are the biofilm

The act as barrier to antibiotic penetration and host defences. once mature they disperse individual bacteria and dissiminate the disease.
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Old 06-04-2013
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Quote:
Originally Posted by aman_j View Post
E. is the answer. Its the biofilm that helps it to bind to the shunt. Read a similar question in kaplan
You are right!!
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  #26  
Old 06-04-2013
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other biofilm prod organisms....

1)strep. mutans & sanguinis - dental plaques
2)p. aeruginosa - cystic fibrosis pneumonia/ contact lens
3)viridans strep - endocarditis
4)Nontypable H.influenza - otitis media

Doubt- what does it mean- nontypable?? like a strain??
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  #27  
Old 06-04-2013
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Non typable means no capsule so u cant type(find the subclass) .... HiB is the typable one that causes pnemonia and can be protected by vaccination but otitis media due to non typbale heam. Influenza is not protected by vaccine since it lacks the capsule against which the antibody is made
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  #28  
Old 06-04-2013
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hi,
have you started doing the mock tests and all?? like uworld sim tests ... or nbmes??

When is the right time to start??
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  #29  
Old 06-04-2013
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My plan is to finish pharma and then do FA once . Then take Nbme and uworld and then do a diffrent nbme next month... Something like that havnt thought that far ahead.
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  #30  
Old 06-04-2013
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For me I have been busy with the ER shifts, its really pain in the ,,,..

once I'm free and I have the time, I think I will do one of the NBME so I know my weakness early on and I have the time to correct them

Most people say, do simulation and NBME at least once or twice,so if I have the time now, why to be lazy about it.
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Old 06-05-2013
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hmmm... ok thanks for the advice.
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ok qs for today...Infant born to 28 yr old female expresses shrill cry, sneezing, rhinorrhoea, tremor and diarrhoea accompanied by myoclonic jerks progressing to seizures.patient's mother lives in the streets and has had no prenatal care...what will control the patients symptoms-

1)naloxone
2)flumazenil
3)tincture of opium
4)folic acid
5)vit k
6)NaHCO3
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  #33  
Old 06-05-2013
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Is it A? Wow thats a tough one ... Symptoms of withdrawal in an infant seriously?
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Old 06-05-2013
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Is it A?
Naloxone would b appropriate?
__________________
kill the MLE.....
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Quote:
Originally Posted by aman_j View Post
Is it A? Wow thats a tough one ... Symptoms of withdrawal in an infant seriously?
I know right?? That's why I put it up here.... but a) is not the answer...
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  #36  
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the answer is 3)tincture of opium

Since the mother is homless and with no prenatal care.... she probably has chance of polydrug abuse....
symptoms of opium withdrawal- begin 24-48 hrs after birth but mainly depend on mother's last dose...

treatment is opium solution....

Naloxone is an opioid receptor antagonist- used to treat intoxication... given in withdrawal it worsens symptoms....

Well now we can answer if it comes in the exam..... a point for us
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Old 06-05-2013
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Q. A pt. with DVT being treated with heparin presents to the ER with bleeding from the nose. To counter the effect of the heparin the physician decides to use protamine. What is the moa of protamine .
A. Competitive antagonist
B. physiological antagonist
C. Chemical antagonist
D. Non competitive antagonist
E. decreases potency of heparin
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  #38  
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Quote:
Originally Posted by aman_j View Post
Q. A pt. with DVT being treated with heparin presents to the ER with bleeding from the nose. To counter the effect of the heparin the physician decides to use protamine. What is the moa of protamine .
A. Competitive antagonist
B. physiological antagonist
C. Chemical antagonist
D. Non competitive antagonist
E. decreases potency of heparin
C) chemical antagonism....
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  #39  
Old 06-06-2013
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Yup thats correct
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qs:
4-yr old boy- brought to physician because of fever lasting 5 days.irritable with 2-3 episodes of vomiting.he has-T-102f, bilateral conjunctivitis, bright red tongue with cracked lips, desquamation of skin of fingertips
Which of the following complications is he at risk of developing-

1)proliferative glomerulonephritis
2)aortic dissection
3)pulmonary cavities
4)coronary artery aneurysm
5)monoocular blindness
6)mononeuritis multiplex
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  #41  
Old 06-06-2013
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Question August taker

Hey guys,
i'm planing to take it on august too but i'm afraid coz i lost a lot of time and now i have less than 3 months,anyway i have read kaplan once and i dont have time to do it again and i did FA once and now im doing the kaplan qbank and then i will try to take an NBME exam to see my progress then do FA for the second time then do the uworld then FA for the third and nbme again and finally i want to finish with uworld, so what do you think guys i really appreciate your opinions and suggestions.
Btw r you doing kaplan qbank just high yield or all?and is it necessary to do the fredv2 step1 practice from usmle.org?

Thanks for this nice Thread.
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Quote:
Originally Posted by vinaya View Post
qs:
4-yr old boy- brought to physician because of fever lasting 5 days.irritable with 2-3 episodes of vomiting.he has-T-102f, bilateral conjunctivitis, bright red tongue with cracked lips, desquamation of skin of fingertips
Which of the following complications is he at risk of developing-

1)proliferative glomerulonephritis
2)aortic dissection
3)pulmonary cavities
4)coronary artery aneurysm
5)monoocular blindness
6)mononeuritis multiplex
4) coronary artery aneurysm .... Kawasaki ds
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Old 06-06-2013
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hi,

Can someone please explain this lac operan sequence of e coli and why its so important.... there are quite a number of qs based on this....
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Quote:
Originally Posted by aman_j View Post
4) coronary artery aneurysm .... Kawasaki ds
you are right... nice... i thought of scarlet fever and put glomerulonephritis but scarlet fever doesnt have conjunctivitis and persistent fever....
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Also no mention of sore throat and the exfoliation is in the hands which is characterstic of kawasaki
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Quote:
Originally Posted by Dr.valoxib View Post
Hey guys,
i'm planing to take it on august too but i'm afraid coz i lost a lot of time and now i have less than 3 months,anyway i have read kaplan once and i dont have time to do it again and i did FA once and now im doing the kaplan qbank and then i will try to take an NBME exam to see my progress then do FA for the second time then do the uworld then FA for the third and nbme again and finally i want to finish with uworld, so what do you think guys i really appreciate your opinions and suggestions.
Btw r you doing kaplan qbank just high yield or all?and is it necessary to do the fredv2 step1 practice from usmle.org?

Thanks for this nice Thread.
hey your idea seems good enough. it depends on your score in the tests i guess to decide if you need to do revise more or not... the first aid team keeps advising to do as many qs as possible... so why not that step 1 practice... lets see what others say...
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Quote:
Originally Posted by aman_j View Post
Also no mention of sore throat and the exfoliation is in the hands which is characterstic of kawasaki
Ohhh yeahhh... the strawberry tongue fooled me.. should be more careful next time...
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Q. A 42 yr old male with 3 episodes of anorexia , anhedonia and depressed mood and a single episode of excessive spending,gambling and euphoria in the past 2 yrs under treatment developed polyuria and polydipsia with Uosm=150mosm ... The next step in management would be
A: stop the offending agent
B. desmopressin
C. Demeclocycline
D.amilirone
E. hydrochlothiazide
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Quote:
Originally Posted by aman_j View Post
Q. A 42 yr old male with 3 episodes of anorexia , anhedonia and depressed mood and a single episode of excessive spending,gambling and euphoria in the past 2 yrs under treatment developed polyuria and polydipsia with Uosm=150mosm ... The next step in management would be
A: stop the offending agent
B. desmopressin
C. Demeclocycline
D.amilirone
E. hydrochlothiazide

E. hydrochlorothiazide .. ?
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stop the offending drug?? he must be taking lithium as treatment i think.

btw, nice thread..
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Quote:
Originally Posted by aman_j View Post
Q. A 42 yr old male with 3 episodes of anorexia , anhedonia and depressed mood and a single episode of excessive spending,gambling and euphoria in the past 2 yrs under treatment developed polyuria and polydipsia with Uosm=150mosm ... The next step in management would be
A: stop the offending agent
B. desmopressin
C. Demeclocycline
D.amilirone
E. hydrochlothiazide
A)Stop the offending drug....
he is taking lithium for bipolar disorder... that causes nephrogenic diabetes insipidus....right?
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so why isnt tetracycline to be taken with dairy or other vitamin supplements??
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hey guys what do you think are the topics we will forget and probably should take note of before the exams?? i want to make a list so that if found we can put up a pic or pdf file or something and we can print them all out and have it handy......
I think lysosomal storage disorders, glycogen storage diseases, g protein receptor mech., ??
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Guys the answer to the Q i put up is D.
In all other cases of NDI treat with THIAZIDE except when due to lithium. With NDI due to lithium treat with weak diuretic.
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Quote:
Originally Posted by vinaya View Post
hey guys what do you think are the topics we will forget and probably should take note of before the exams?? i want to make a list so that if found we can put up a pic or pdf file or something and we can print them all out and have it handy......
I think lysosomal storage disorders, glycogen storage diseases, g protein receptor mech., ??
What about activators ans inhibitors of enzymes .... Widely tested and very confusing when taken all together
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34 yr old female,difficulty in tasting food, past few weeks food tastes bland to her, cannot differentiate if its sour, sweet or salty, her husband is concerned coz he noticed her facial movements to be odd lately, which may be just as a result of her taste problem, they consult a neurologist who, after history and PE, suspects a lesion in one of the nerves tat makes up the solitary tract.

In addition to the loss of taste, what other PE findings would this patient have?
A) dry mouth
B) hemiparalysis of the tongue
C) impaired hearing
D) impaired pain and sensation in the tongue
E) impaired smell
F) weakness in the muscles of mastication
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Quote:
Originally Posted by aman_j View Post
Guys the answer to the Q i put up is D.
In all other cases of NDI treat with THIAZIDE except when due to lithium. With NDI due to lithium treat with weak diuretic.
I think it is amiloride. Amilirone sounds like amrinone which is a CCB. Is this a question you came up with or did u find it somewhere??
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Amiloride is a k sparing diuretic... Sorry guys typo error...
Came across the question somewhr
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Quote:
Originally Posted by usmlestep1taker View Post
34 yr old female,difficulty in tasting food, past few weeks food tastes bland to her, cannot differentiate if its sour, sweet or salty, her husband is concerned coz he noticed her facial movements to be odd lately, which may be just as a result of her taste problem, they consult a neurologist who, after history and PE, suspects a lesion in one of the nerves tat makes up the solitary tract.

In addition to the loss of taste, what other PE findings would this patient have?
A) dry mouth
B) hemiparalysis of the tongue
C) impaired hearing
D) impaired pain and sensation in the tongue
E) impaired smell
F) weakness in the muscles of mastication


C: impaired hearing : hyperacusis due to facial nerve lesion...
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answer is cc
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Quote:
Originally Posted by usmlestep1taker View Post
34 yr old female,difficulty in tasting food, past few weeks food tastes bland to her, cannot differentiate if its sour, sweet or salty, her husband is concerned coz he noticed her facial movements to be odd lately, which may be just as a result of her taste problem, they consult a neurologist who, after history and PE, suspects a lesion in one of the nerves tat makes up the solitary tract.

In addition to the loss of taste, what other PE findings would this patient have?
A) dry mouth
B) hemiparalysis of the tongue
C) impaired hearing
D) impaired pain and sensation in the tongue
E) impaired smell
F) weakness in the muscles of mastication

Answer is A) dry mouth,
Facial nerve is affected in this patient, and facial nerve innervates submandibular and sublingual salivary glands, so facial nerve lesion will cause dry mouth.

Hyperacusis is the right answer too, which occurs with facial nerve lesion, i too was confused with that, may be what they mentioned as impaired hearing is to mean hearing loss. In that case impaired hearing would be a wrong answer.
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I considered dry mouth aswell but parotid via glossopharyngeal n is still active so i dont understand how just facial nerve palsy could cause dry mouth ... Moreover drooling from affected site is one feature of facial nerve palsy... Also impaired hearing could mean both hyperacusis or hearing loss
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I must say guys this is an amazing thread.... I'm also lookin to give exam in august... With al the prometric issues in India iv had a horrible time the past few months... So iv ended having to reapply.... Quick question... Anybody with similar issue? Reapplyin creates no problems on your resume right? And its not an attempt or anythin Like that right? M sorry if my questions are dumb... Just been worried since this was sudden... Thank you guys in advance....
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Quote:
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I must say guys this is an amazing thread.... I'm also lookin to give exam in august... With al the prometric issues in India iv had a horrible time the past few months... So iv ended having to reapply.... Quick question... Anybody with similar issue? Reapplyin creates no problems on your resume right? And its not an attempt or anythin Like that right? M sorry if my questions are dumb... Just been worried since this was sudden... Thank you guys in advance....

hi what kind of issues did u have with prometric....?? The centres are available only at hyd, gurgaon and allahabad... is there any chance others will open?? i guess unless you have actually written an exam its not counted as an attempt ...... could it??
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lysosomal storage disorders
Upper limb nerves
Lower limb nerves
Glycogen storage disorders
Vitamins deficiencies
Drugs of abuse
CD molecules and the significance of each
Tumor suppressor genes
Oncogenic Translocations
Bone tumors
G protein receptors types and hormone examples
Diffusion limited versus perfusion limited
Steroid synthesis and adrenal cortex pathways
Exotoxins
Streptococci and Staphylococci characteristics
Antibiotic mechanism of actions
Rickettsia
Parasites (all of them)
Leukocyte/endothelium interaction
Sleep stages with their EEG changes
Hemoglobin synthesis pathway and porphyria
MEN Types
Cardiomyopathy types
Teratogenic drugs
Muscarininc and Adrenergic lists
The glomerulonephritis histopathologic changes
Bone tumors
Leukemias
Inducers and Inhibitors
HLA Associations
Hypothalamic nuclei
List of antivirals and their mode of action
List of viral classes and their exceptions
Purines and Pyrimidines pathways
Monoclonal antibodies and anticancer drugs
Autoantibodies
CD counts landmarks in HIV infection
Pharyngeal arches and pouches and their derivatives
Antiarrhythmics classes

Found this list on uworld............ thank you RASHEED ....
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Hey guys planning on taking an NBME next week just to see whr i am with my prep ... Any ideas as to what Nbme to take and also can we pay them through debit card
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Unhappy how to study biochem

hi...im taking step 1 in 2nd week of august...i went thru fa once.halfway thru my second reading...did 40%of uworld....i know nothing of biochem...suggest how i go about studying biochem at dis point....
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im doing the exam in August,

I finsished antomy histo nueruanatomy embryo
and pharma and patho

from books and from FA also

I did UW for those subjects and i finished 60% of UW

I watched all kaplan videos for these subjects

I finished genetics from kaplan and micro from MRS but i need to reread them

I watched all videos for pharma

what do u think about my progress???

my aim was 260+ but with each day that passes I lose confidence
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Default Well done

well done guys.. keep it up... and keep oine another motivated.
i am also giving the step 1 in august.
i'll follow this thread to keep myself updated

Thank you everyone.

Hey . Does any of you have any idea about other helpful sources of genetics ???.... because i am little weak at genetics portion of biochem. i need to practice those '"prevalence and carrier frequency problems"...
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Quote:
Originally Posted by aman_j View Post
Hey guys planning on taking an NBME next week just to see whr i am with my prep ... Any ideas as to what Nbme to take and also can we pay them through debit card
hey there are threads in uworld that does a poll on nbme and discusses the exams like which are easier and tougher and all.... you should read those.....
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Quote:
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hi...im taking step 1 in 2nd week of august...i went thru fa once.halfway thru my second reading...did 40%of uworld....i know nothing of biochem...suggest how i go about studying biochem at dis point....
hey you have read a lot!! have you tried the kaplan videos? they are very informative once you get past the boredom.... and you know get used to it...
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qs:

A 65 yr old male has a mitral valve replacement. he presents with low grade fever, dyspnoea and malaise. the bacteria isolated from multiple blood cultures is g+ve cocci in clusters which is catalase +ve coagulase -ve. which is the best antibiotic to be used.

1)penicillin G
2)nafcillin
3)vancomycin
4)ceftrioxone
5)erythromycin
6)ciprofloxacin
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Correct Answer Vancomycin

The bacteria is S. epidermidis. Rx of choice is Vancomycin.
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a 45 yr old male comes in with palpitations and fatigue. he is a smoker- 1pack/day and occasional alcohol. his bp is 110/70 mmhg and hr- 120bpm. pulse- irregularly irregular. he is given digoxin and his hr drops to 85bpm and irregular. what is the moa of digoxin here.

1) incr ventricular contractility
2) incr. atrial refractoriness
3)decr. action potential duration
4)incr parasym. tone
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Quote:
Originally Posted by vinaya View Post
a 45 yr old male comes in with palpitations and fatigue. he is a smoker- 1pack/day and occasional alcohol. his bp is 110/70 mmhg and hr- 120bpm. pulse- irregularly irregular. he is given digoxin and his hr drops to 85bpm and irregular. what is the moa of digoxin here.

1) incr ventricular contractility
2) incr. atrial refractoriness
3)decr. action potential duration
4)incr parasym. tone

increase parasympathetic tone?
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Quote:
Originally Posted by vinaya View Post
qs:

A 65 yr old male has a mitral valve replacement. he presents with low grade fever, dyspnoea and malaise. the bacteria isolated from multiple blood cultures is g+ve cocci in clusters which is catalase +ve coagulase -ve. which is the best antibiotic to be used.

1)penicillin G
2)nafcillin
3)vancomycin
4)ceftrioxone
5)erythromycin
6)ciprofloxacin

vancomycin?
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Quote:
Originally Posted by vinaya View Post
a 45 yr old male comes in with palpitations and fatigue. he is a smoker- 1pack/day and occasional alcohol. his bp is 110/70 mmhg and hr- 120bpm. pulse- irregularly irregular. he is given digoxin and his hr drops to 85bpm and irregular. what is the moa of digoxin here.

1) incr ventricular contractility
2) incr. atrial refractoriness
3)decr. action potential duration
4)incr parasym. tone
Digoxin exerts an AV blockage via the vagotonic effect so the answer is 4)
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wow, all of you are geniuses...

The correct answers are.... vancomycin for my first qs
incr. parasympathetic tone for second qs...
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By the way staph epidermidis also utilises the biofilm production mechanism right?
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Q: a 43 y/o female comes to the ER with diplopia and bilateral proptosis. She also gives a H/O weight loss and palpitation in the past 2 mo. on P/e her bp is 120/90 and her HR is 120 bpm. She is afebrile. The physician prescribes certain medication and 2 weeks later the pt. returns with decrease in proptosis . The mechanism of the drug prescribed is
A. Sympathetic receptor antagonist
B. blockage of iodide uptake
C. Anti inflammatory
D. Inhibit peripheral conversion of t4 to t3
E. Inhibit thyroid hormone synthesis
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Quote:
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By the way staph epidermidis also utilises the biofilm production mechanism right?
Ya along with strep mutans and few others h. Inflenza as well
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Quote:
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Q: a 43 y/o female comes to the ER with diplopia and bilateral proptosis. She also gives a H/O weight loss and palpitation in the past 2 mo. on P/e her bp is 120/90 and her HR is 120 bpm. She is afebrile. The physician prescribes certain medication and 2 weeks later the pt. returns with decrease in proptosis . The mechanism of the drug prescribed is
A. Sympathetic receptor antagonist
B. blockage of iodide uptake
C. Anti inflammatory
D. Inhibit peripheral conversion of t4 to t3
E. Inhibit thyroid hormone synthesis

E. inhibit thyroid hormone synthesis?
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Correct Answer

C - Anti-inflammatory (Ophthalmopathy in Hyperthyroidism is treated with high dose glucocorticoids)
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Quote:
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C - Anti-inflammatory (Ophthalmopathy in Hyperthyroidism is treated with high dose glucocorticoids)
Thats correct
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24 year old man brought to ED with change in mental status. PE reveal fever, dysarthric patient with retinal hemorrhage and puncture mark on left forearm. auscultation reveal murmur. blood culture show gram positive catalas negative organisms. which culture condition can help identify single causative organism

a. absence of colonies in presence of penecillin.
b. growth in 6.5% nacl
c. growth in presence of optochin
d. soluble in bile
e. growth in chocolate agar
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Quote:
Originally Posted by saleem khawaja View Post
24 year old man brought to ED with change in mental status. PE reveal fever, dysarthric patient with retinal hemorrhage and puncture mark on left forearm. auscultation reveal murmur. blood culture show gram positive catalas negative organisms. which culture condition can help identify single causative organism

a. absence of colonies in presence of penecillin.
b. growth in 6.5% nacl
c. growth in presence of optochin
d. soluble in bile
e. growth in chocolate agar
C : for strep viridans
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Quote:
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C : for strep viridans
this scenario represents SBE. wat organisms in strep family cause SBE?
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this scenario represents SBE. wat organisms in strep family cause SBE?
Streptococcus viridans ex. S. mutans etc... They are the commonest cause of SBE
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Streptococcus viridans ex. S. mutans etc... They are the commonest cause of SBE
Group D enterococal strep particularly Enterococus fecalis also causes SBE
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Originally Posted by saleem khawaja View Post
24 year old man brought to ED with change in mental status. PE reveal fever, dysarthric patient with retinal hemorrhage and puncture mark on left forearm. auscultation reveal murmur. blood culture show gram positive catalas negative organisms. which culture condition can help identify single causative organism

a. absence of colonies in presence of penecillin.
b. growth in 6.5% nacl
c. growth in presence of optochin
d. soluble in bile
e. growth in chocolate agar
answer is b, growth in 6.5% nacl
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  #91  
Old 06-11-2013
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There are no risk factors for enterococcal bacteria... Portal of entry for enterococcal bacteria is diffrent than that of strep . Whats your source?
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  #92  
Old 06-11-2013
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Originally Posted by aman_j View Post
There are no risk factors for enterococcal bacteria... Portal of entry for enterococcal bacteria is diffrent than that of strep . Whats your source?
I agree but question is asking about best medium to differentiate streptococci that cause SBE. both viridans and enterococi are optochin resistant and bile insoluble, but only enterococi can grow in 6.5% nacl
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  #93  
Old 06-11-2013
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"RULE OF"s in medicine-
1) RULE OF 2s on MECKEL'S DIVERTICULUM-

2% of population
2 feet from ileocaecal valve
2 inches in length
2% symptomatic
2 times more common in males

2)RULE OF 2s IN 2nd WEEK OF GESTATION-

2 cavities- amniotic cavity, yolk sac
2 layers- epiblast, hypoblast
2 components of placenta- cyto, syntiotrophoblast

3) RULE OF 3s IN 3rd WEEK-

3 germ layers- ecto, meso, endoderm

4) RULE OF 4s IN 4th WEEK-

4 chambers in heart
4 limb buds
anything else you guys can think of??
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  #94  
Old 06-11-2013
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Quote:
Originally Posted by vinaya View Post
"RULE OF"s in medicine-
1) RULE OF 2s on MECKEL'S DIVERTICULUM-

2% of population
2 feet from ileocaecal valve
2 inches in length
2% symptomatic
2 times more common in males

2)RULE OF 2s IN 2nd WEEK OF GESTATION-

2 cavities- amniotic cavity, yolk sac
2 layers- epiblast, hypoblast
2 components of placenta- cyto, syntiotrophoblast

3) RULE OF 3s IN 3rd WEEK-

3 germ layers- ecto, meso, endoderm

4) RULE OF 4s IN 4th WEEK-

4 chambers in heart
4 limb buds
anything else you guys can think of??
Rule of 10 in pheochromocytome
10% b/l
10% extra adrenal
Less than 10% malignant
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  #95  
Old 06-11-2013
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rule of 2 in child development
At 2 year age baby can speak 200 words and 2 words sentences
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  #96  
Old 06-11-2013
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Exam on 14 Aug

Doing Biochem now ,, really tired from studying day and night

I'm having some kind of anxiety ...there are alot of kaplan videos and I can't keep up with my scheduled subjects

I finished Physio and anatomy but there are some videos that I missed so I can keep up with my schedual

for instance I missed Renal Phys alot of it and Endo
and Genital system and GIT on anatomy

and think these are HY stuff

now I'm doing biochem I finished all the molecular stuff except for tech. and started on metabolism but there are about 34 videos

any advise or comment =( ?
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  #97  
Old 06-11-2013
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Quote:
Originally Posted by Dr. Egocentric View Post
Exam on 14 Aug

Doing Biochem now ,, really tired from studying day and night

I'm having some kind of anxiety ...there are alot of kaplan videos and I can't keep up with my scheduled subjects

I finished Physio and anatomy but there are some videos that I missed so I can keep up with my schedual

for instance I missed Renal Phys alot of it and Endo
and Genital system and GIT on anatomy

and think these are HY stuff

now I'm doing biochem I finished all the molecular stuff except for tech. and started on metabolism but there are about 34 videos

any advise or comment =( ?
hi, well first of all you are doing good.... no one keep up schedules... i have one printed up and put on my door every week... and max i tick off 2-3 of the plan.... so you are not alone in that.... and biochem well they are imp so i would suggest not to skip any of the videos... lots of extra points in between i felt....
maybe you should mix it up.... like biochem morning... some easier sub evening... i mix anat with pharm now anat is easier... that helps...
hmmm... anyone else??
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  #98  
Old 06-11-2013
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Quote:
Originally Posted by vinaya View Post
hi, well first of all you are doing good.... no one keep up schedules... i have one printed up and put on my door every week... and max i tick off 2-3 of the plan.... so you are not alone in that.... and biochem well they are imp so i would suggest not to skip any of the videos... lots of extra points in between i felt....
maybe you should mix it up.... like biochem morning... some easier sub evening... i mix anat with pharm now anat is easier... that helps...
hmmm... anyone else??
Good to know that I'm not the only one who is lagging behind =)

I started to think of postponing my exam until I finish everything

but since I'm not the only one,, that's really relieving


about anatomy, I think of myself as future surgeon, but each time I do anatomy questions on Uworld my grade gets lower and lower ><
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  #99  
Old 06-11-2013
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hello...how are u guys studying?..like how many hours are u putting in?...i get so distracted...need motivation..help
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  #100  
Old 06-11-2013
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Can anybody comment on my previous comment

that will help alot

I am very disperate and need motivation
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