1)Why rbc count increases in thalasemia and how mcv and hematocrit decrease ?
2)In cooleys anemia rbc with alpha inclusions are removed by liver macrophage why? We know hbf (2alpha & 2gamma chains)is in fetal it also has alpha then why macrophage dont remove these alpha chains?
2)In cooleys anemia rbc with alpha inclusions are removed by liver macrophage why? We know hbf (2alpha & 2gamma chains)is in fetal it also has alpha then why macrophage dont remove these alpha chains?