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Old 06-10-2013
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Drug Beta 2 agonist increase insulin or glucagon?

I have read everywhere that it actually increase insulin BUT if it increase insulin then how it also cuz glycogenolysis??
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Old 06-10-2013
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learn this, it will come in your exam
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Old 06-10-2013
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It increases all insulin , glucagon , and glycogenoylsis by liver and muscle, and this makes sense considering the FIGHT-FLIGHT response in sympathetic nervous system , if you are running u need more glucose in ur blood to be available to cells by glycogenylisis and glucagon , and at the same time u need more glucose to enter ur cells by insulin
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Old 06-11-2013
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Seliac it makes sense BUT in kaplan only insulin is written not glucagon
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Old 06-11-2013
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Quote:
Originally Posted by medicalbiology View Post
I have read everywhere that it actually increase insulin BUT if it increase insulin then how it also cuz glycogenolysis??
BETA 2 Agonist increases cAMP ,glucagon, glycogenolysis, insulin all it does care about anything it wants the cell to have energy
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Seliac it makes sense BUT in kaplan only insulin is written not glucagon
dude I am sure 100 % I have read it in lippincott pharmacology during colleague
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Old 12-08-2013
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In "J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S313-7 " it does say beta agonists promote increased insulin, glucagon, glucose in blood preventing hypoglycemia, thermogenesis as well as lipolysis
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Old 12-08-2013
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There are only two concrete things I know about it:

1. Dr Lionel Raymon mentioned in the ANS pharmacology that a little but not significant amount of insulin is released during fight flight fright response in order to let cells uptake glucose through insulin dependent GLUT 4 channels and burn it down to ATPs and not store it.

2. A beta 2 block will worsen the symptoms of hypoglycemia if a patient with DM overdosed themselves with insulin coz beta 2 receptors usually facilitate anti insulin metabolic effects, so their block is pro-insulin and helpful in hypoglycemia.
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