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CSF Protein and Glucose in Meningitis; Why?

4K views 3 replies 3 participants last post by  seliac 
#1 ·
hi.

Haven't got really understood how high protein! and low glucose in CSF in pat
with Meningitis come. and why is it different in case with infection with virus.

Is there anyone who can clarify it for me!:redcheeks;
Thanks in advance.
 
#2 ·
protein is elevated and glucose in decreased in bacterial meningitis
Viral meningitis normal or slightly decrease

for protein the source of the increase is the bacteria its self which contains high protein in their composition so an increase in protein indicated that there is replicating bacteria , another source is the high large increase in inflammatory cells ( in virus not large increase) these cells contain high protein content

for Glucose , bacteria feed on glucose decreasing it , also due to inflammation , the BBB will become impermeable to glucose causing decrease in glucose level ( in virus the inflammation is not enough to make the barrier impearable )
 
#3 ·
protein is elevated and glucose in decreased in bacterial meningitis
Viral meningitis normal or slightly decrease

for protein the source of the increase is the bacteria its self which contains high protein in their composition so an increase in protein indicated that there is replicating bacteria , another source is the high large increase in inflammatory cells ( in virus not large increase) these cells contain high protein content

for Glucose , bacteria feed on glucose decreasing it , also due to inflammation , the BBB will become impermeable to glucose causing decrease in glucose level ( in virus the inflammation is not enough to make the barrier impearable )
Hmm bacterial eating glucose!:))
 
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