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Old 06-22-2013
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Immunology Conjugated Vaccines; T Cell or B Cell

Can someone explain if conjugated vaccines (like HiB) activate T cells? I thought that the whole point of conjugation is to induce T cells, which can allow class switching and generate long term antibodies. If the vaccine is only activating B cells, we would only get IgM, which doesn't last that long.

Found 2 UW qs that say HiB induces humor immunity and not CMI!!???
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Old 06-22-2013
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Humoral immunity is igG ... For any kind of immunity t cells have to activated.... If u read kaplan immunology > after tcells are activated then u can either have a th1 responce leading to cmi or a th2 response leading to humoral immunity... I dont see why you are confused
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