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Old 07-06-2013
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Biochemistry leucine lysine in PDH deficiency

what is rationale of giving leucine and lysine in Pyruvate dehydrogenase deifciency as mentioned in first aid pg 101 ?
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Old 07-06-2013
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Because of PDH deficiency pyruvate will be shunted to lactate pathway and then to gluconeogensis... Leucine and lysine are purely ketogenic ... They will prevent lactate formation
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