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Old 07-23-2013
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Default alpha 1 and beta blockers in Pheochromocytoma

Why is it important to give Beta blockers AFTER alpha blockers?

Why is it not a good idea to use beta blockers first, and then alpha blockers?

OK, nvm.... wouldn't make sense to add the beta blocker first, because the increased EPI would still have vasoconstriction effect on all the alpha 1 receptors. first irreversibly block alpha 1. and then, if needed, add beta blocker to slow down the heart. makes perfect sense.
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Old 06-20-2014
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Beta blockers are used if significant tachycardia occurs after alpha blockade. Beta blockers are not administered until adequate alpha blockade has been established, however, because unopposed alpha-adrenergic receptor stimulation can precipitate a hypertensive crisis. Noncardioselective beta blockers, such as propranolol (Inderal) or nadolol (Corgard), are the usual choice; however, cardioselective agents, such as atenolol (Tenormin) and metoprolol (Lopressor), also may be used.
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