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Old 08-25-2013
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Default 12 yo boy with renal failure

12 year-old boy has had slowly progressive renal failure for the past 2 years. He is short and pale. Serum calcium concentrations is decreased and serum phosphate, BUN, creatinine concentration are increased. X-rays of the bones show subperiosteal erosions of the phalanges, osteopenia, and coarsening trabeculae. Whicj of the following sets of laboratory findings in serum is most likely in this pt?

25-hydroxycholecalciferol 1,25-dyhydroxycholecalciferol PTH
a. decrease normal decrease
b. normal d n
c. increase i i
d. d n i
e. n d i
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Old 08-25-2013
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E..............he has renal osteodystrophy so increased Phosphate(renal damaged cant excrete it normally) so that causes increase in PTH . PTH also activates 1 a hydroxylase in kidneys to convert vit D in its active form (1-25 hydrox) but in renal failure that doesn't work good so it is decreased

Last edited by MishkaMD; 08-25-2013 at 01:47 PM.
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Old 08-25-2013
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Normal decrease increase
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E the answer
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