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Old 09-06-2013
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Default Quinidine

hi,
from FA 2013, it states that quinidine is a P450 inhibitor however, from DIT, they said it's a inducer... which one is correct..?
thanks
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Old 09-06-2013
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Quinidine is a P450 inhibitor.

The way I remember this is that QuiniDine "Quiets Down" P450.

Never trust DIT over FA.
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Old 09-06-2013
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2012 fa says it is both inducer and inhibitor. but the predominant action is induction... also remember quinidine displaces digoxin from its binding site and leads to toxicity. i guess the latter fact is more relevant to know .
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