Mechanism of Metabolic Acidosis in Chlorine Toxicity? - USMLE Forums
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Old 09-22-2013
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Poison Mechanism of Metabolic Acidosis in Chlorine Toxicity?

how does chlorine toxicity cause metabolic acidosis...mechanism??

thanks
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Old 09-22-2013
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Chlorine toxicity doesn't cause metabolic acidosis. Hyperchloremia is the laboratory finding seen in normal anion gap metabolic acidosis (eg: RTA, diarrhea).
Hope that helps.
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Old 09-22-2013
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Na-(Cl+HCO3)=12
whenever you get excessive Cl your body tries to maintain electrical equilibrium therefore gets rid of HCO3 or Na-(increased Cl+decreased HCO3)=12
decreased HCO3 with normal anion gap (12)=non anion gap metabolic acidosis
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