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Old 11-12-2013
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Bacteria Neisseria Capsule versus Pilus!

I'm a little bit confused here. Vaccines for nisseria are aimed at the capsules. SO this means that if the capsule changes, the vaccine will also need to be changed.

I was reading somethig in UWorld and I came across that nisseria also changes the antigens in its Pilus (which it uses for infection). Is there a vaccine against the pilus, or is it just a vaccine against the capsule? Aren't both, the Pilus and the Capsule picked up as antigens by the body?
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Old 11-12-2013
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Capsule only in neisseria meningitidis, no capsule in n. gonorrhea

and both neisseria meminigitidis and gonorrhoea have pilus and bcz pilus has rapid antigenic variation( it changes ) no vaccination aganist .

and the capsule have no antigenic variation (it doesn't change) like pilus so vaccination only aganist N. memningitidis

i hope it is clear for you now .
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Old 11-13-2013
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Thank you for explaining!
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