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Old 11-14-2013
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Biochemistry Glucocorticoids increase protein synthesis in the Liver!

According to uworld glucocorticoids have catabolic functions BUT it increase protein synthesis in liver...

How it is possible it actually promote glucoNEOgenesis means breakdown of proteins but on other hand uworld saying it increase protein synthsis in liver...
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I think thats also written down in the explanation that they increase protein synthesis so that it can be used in stressful situations.. even i got confused on that, but unfortunately i dont have time for all these why's or what's
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thats just the way they are; they promote catabolism elsewhere, but in the liver specifically, they increase protein synthesis. Thats how gluconeogenesis gets going; you need something to turn that on. Glucocorticoids antagonize the effects of Insulin.
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Originally Posted by abeer View Post
i think thats also written down in the explnation that they increase protein synthesis so that it can be used in stressful situations.. even i got confused on that, but unfortunately i dont have time for all these why's or what's
if you have the kaplan biochemistry notes, chapter 9 shows the process of second messanging for gluconeogenesis, it makes sense after that.
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Originally Posted by CisternaChyli View Post
if you have the kaplan biochemistry notes, chapter 9 shows the process of second messanging for gluconeogenesis, it makes sense after that.

yes i have them, haven't look at them since long as exam is too close, but will see them,
thanx man..
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thanxz abeer and cisterna..
U mean that gluconeogenesis(catabolism of protein) and protein synthesis occur simultaneously in liver?
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Originally Posted by medicalbiology View Post
thanxz abeer and cisterna..
U mean that gluconeogenesis(catabolism of protein) and protein synthesis occur simultaneously in liver?
think about it this way; the proteins that are being synthesized are the enzymes necessary for gluconeogenesis to get going...and then, after that, gluconeogenesis can proceed to catabolize the protein in order to get glucose.
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Originally Posted by abeer View Post
yes i have them, haven't look at them since long as exam is too close, but will see them,
thanx man..
my exam is next friday , but i have my kaplan books open all the time lol
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