Can you guess which virus? - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 12-10-2010
USMLE Forums Guru
 
Steps History: Step 1 Only
Posts: 487
Threads: 95
Thanked 1,458 Times in 356 Posts
Reputation: 1468
Virus Can you guess which virus?

A 19-year-old white male presents to the infirmary complaining of pharyngitis, rhinorrhea, and intermittent wheezing. Pertinent social history includes enlistment in the U.S. Army two months ago, and the patient is currently stationed at Fort Bragg, North Carolina. A physical exam reveals injected conjunctivae bilaterally and diffuse wheezing bilaterally on pulmonary auscultation. Positive cold agglutinin reaction is noted. A virus is isolated in cell culture, and further evaluation reveals a non-enveloped virus with double-stranded linear DNA. Which of the following statements is correct, concerning this viral infection and neoplasia?

A This viral infection is linked to Burkitt's lymphoma
B This viral infection can cause progressive multifocal leukoencephalopathy.
C This viral infection is linked to hepatocellular carcinoma.
D This viral infection is linked to histiocytoma.
E Infection by certain serotypes may cause sarcoma.
F This viral infection is linked to nasopharyngeal carcinoma.
Reply With Quote Quick reply to this message
The above post was thanked by:
ashishkabir (12-11-2010), confident pace (12-11-2010)



  #2  
Old 12-10-2010
USMLE Forums Addict
 
Steps History: 1 + CK
Posts: 117
Threads: 22
Thanked 28 Times in 15 Posts
Reputation: 38
Default

it seems like adeno virus infection,,,

pt is workin for army,signs of conjunctivitis and resp. distress,,,

but i don know any neoplasia caused by adeno,,
i guess the best answer is B,,,,PML caused by polyoma virus naked dsdna virus(but then question says linear dna ,polyoma and papilloma are circular)
the only dsdna naked viruses are parvo,papova,adeno
Reply With Quote Quick reply to this message
The above post was thanked by:
aktorque (12-11-2010)
  #3  
Old 12-11-2010
USMLE Forums Addict
 
Steps History: 1 + CK
Posts: 116
Threads: 7
Thanked 343 Times in 94 Posts
Reputation: 353
Default

answer is adenovirus.

Adenoviruses are nonenveloped viruses with double-stranded linear DNA and an icosahedral nucleocapsid. They are the only viruses with a fiber protruding from each of the 12 vertices of the capsid. The fiber is the organ of attachment and is a hemagglutinin. When purified free of virions, the fiber is toxic to human cells.

There are 41 known antigenic types; the fiber protein is the main type-specific antigen. All adenoviruses have a common group-specific antigen located on the hexon protein.

Certain serotypes of human adenoviruses (especially 12, 18, and 31) cause sarcomas at the site of injection in laboratory rodents such as newborn hamsters. There is no evidence that adenoviruses cause tumors in humans
Reply With Quote Quick reply to this message
The above post was thanked by:
aktorque (12-11-2010), doc9051 (12-11-2010), rigbbm (06-27-2013), Sabio (12-11-2010)
  #4  
Old 12-11-2010
USMLE Forums Guru
 
Steps History: Step 1 Only
Posts: 487
Threads: 95
Thanked 1,458 Times in 356 Posts
Reputation: 1468
Arrow

Quote:
Originally Posted by drahmednawaz View Post
answer is adenovirus.

Adenoviruses are nonenveloped viruses with double-stranded linear DNA and an icosahedral nucleocapsid. They are the only viruses with a fiber protruding from each of the 12 vertices of the capsid. The fiber is the organ of attachment and is a hemagglutinin. When purified free of virions, the fiber is toxic to human cells.

There are 41 known antigenic types; the fiber protein is the main type-specific antigen. All adenoviruses have a common group-specific antigen located on the hexon protein.

Certain serotypes of human adenoviruses (especially 12, 18, and 31) cause sarcomas at the site of injection in laboratory rodents such as newborn hamsters. There is no evidence that adenoviruses cause tumors in humans
OMG.... You have given a genius explanation for this qn. Thank you so much. The answer is E) Infection by certain serotypes may cause sarcoma. As you said that Adenoviruses do not cause tumors but in recent study said that their certain serotypes can cause malignant in human (ex: sarcomas).
Reply With Quote Quick reply to this message



Reply

Tags
Microbiology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
Which virus cause this skin rash? Farazdaq USMLE Step 1 Forum 9 05-20-2016 03:00 PM
Virus Replication lemontea88 USMLE Step 1 Forum 5 01-11-2011 11:34 PM
virus related question Seetal USMLE Step 1 Forum 7 04-01-2010 11:05 AM
Guess what is this? mary USMLE Step 2 CK Forum 4 10-31-2009 08:27 PM
Human Papilloma Virus Mnemonic Ahmed-USMLE USMLE Step 1 Mnemonics 0 07-31-2009 05:26 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)