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Old 12-29-2013
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Default Amennorhea in menopause n polcystic ovary

we know that level of estrogen decrease in menopause and increase in polycystic ovary disease both lead to amenorrhea..
So does this mean increase and decrease both cause AMENORRHEA??
Similarly in DUB estrogen is increased due to anovulation but it cause bleeding instead of Amenorrhea

Last edited by medicalbiology; 12-29-2013 at 08:31 AM.
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we know that level of estrogen decrease in menopause and increase in polycystic ovary disease both lead to amenorrhea..
So does this mean increase and decrease both cause AMENORRHEA??
Similarly in DUB estrogen is increased due to anovulation but it cause bleeding instead of Amenorrhea
Menstruation involves both normal ovarian function and ability of the endometrial lining to shed. It's true estrogen in in PCOS but decreased in menopause. Remember that the increase in estrogen in PCOS is due to Very high LH relative to FSH. The high LH caused hyperandrogenism and more importantly anovulation (, so bad ovarian function. If u cannot release eggs of course ur uterus cannot shed those tears: menstruation) also in PCOS there is virtually no progesterone and as such no secretory phase.
Remember that the increase in estrogen in PCOS is just due to peripheral aromatisation of androgens. I think the reason in menopause is cool job.

What is full meaning of DUB I think my brain has gone to sleep.
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sudden fall in progesterone level is the reason for menstruation


in both cases theres no ovulation=no corpus luteum and no progesterone-no corpus luteum involution and no fall in progesterone level which is the reason for amenorrhea
in dysfunctional uterine bleeding breakthrough bleeding occurs (which is not menstruation-just proliferated endometrium sheds because theres no stibilizing effects of progesterone)
breakthrough bleeding may occur in PCOS as well and somtimes in postmenopausal female who has increased BMI
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Thankyou nassero n medicalexaminer for detailed reply..
@nassesro DUB is dysfunctional uterine bleeding
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Thankyou nassero n medicalexaminer for detailed reply..
@nassesro DUB is dysfunctional uterine bleeding
U welcome
Yeah I screwed up with DUB.
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