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Old 01-30-2014
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Angry For rapid induction which anesthetic is prefered

High lipid solubilty means high potency...

We know that potency is defined as minimum amount of drug needed to produce desired effect so does this mean high lipid soluble drug(high potency) drug should be used to produce desired effect (i.e rapid induction)..

.BUT we dont use it so why are we calling lipid soluble drug HIGHLY POTENT which actually produce slow induction...
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Old 01-30-2014
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Originally Posted by medicalbiology View Post
High lipid solubilty means high potency...

We know that potency is defined as minimum amount of drug needed to produce desired effect so does this mean high lipid soluble drug(high potency) drug should be used to produce desired effect (i.e rapid induction)..

.BUT we dont use it so why are we calling lipid soluble drug HIGHLY POTENT which actually produce slow induction...
high potency anesthetics are stronger but more lipid soluble which translates into longer period required for anesthesia (first adipose tissues are saturated until the desired plasma concentration is reached=longer process compared to less soluble anesthetics)
+ they remain longer in the body and are not preferred
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