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Old 02-24-2014
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Default Anemia increase or decrease TPR?

i was reading in brs that Anemia cause increase in TPR and also CO BUT kaplan said decrease in TPR because of decrease viscosity ...

For me both logics are true
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Old 02-24-2014
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i never read anywhere anemia can increase tpr. if it does may be it cud be due to increased sympathetic tone in blood loss anemia ? i m only guessing.
the direct effect is obviously decreased viscosity hence decreased tpr leading to inc CO
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Old 02-26-2014
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Resistance = (8*viscosity*length of the vessel)/pi*r^4
So in anemia we have decreased viscosity which would decrease TPR. I believe this is the mechanism of how anemia causes high-output cardiac failure (decreased TPR ==> increased CO but tissues are still hypoxic from anemia; the definition of high-output cardia failure). Hope this helps.
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Old 02-27-2014
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Anemia:

TPR down
HR, SV, CO, Pulse Pressure UP
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