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Old 02-27-2014
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Default membranous nephropathy or DPGN

A 43-year-old woman with systemic lupus erythematosus has nephrotic
syndrome. Examination of renal tissue obtained on biopsy shows a diffuse
proliferative glomerulonephritis with electron-dense deposits along the
glomerular basement membrane. lmmunofluorescent studies show granular
deposits of complement along the basement membrane. Which of the
following is the most likely cause of these findings?

A.Antibodies directed against glomerular basement membrane
B.Antibodies directed against viral antigens expressed on endothelial
C.Anti-DNA/DNA immune complex deposition in glomeruli
D.Autoantibodies to podocyte antigens
E.CD8+ T-lymphocijte cytotoxiclityzolil‘virds-infected mesangial cells

The answer is clear: C
The first sentence said this patient has membranous nephropathy but the second sentence said this patient has DPGN. So does this patient have both type of diseases?
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