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  #1  
Old 01-18-2011
dakshmalhotra's Avatar
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Question Na retention in Hyperinsulinemia

why there is Na retention in c/o hyperinsulinemia ??
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Old 01-18-2011
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I'd like to know as well.
I just know that hyponatremia can be caused by hyperglycemia, hyperlipidemia, or hyperproteinemia.
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Old 01-19-2011
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well i read this stuff in goljan which state this statement...i thought opposite as insulin tend to shift k+ into the cell so Na will come out... i am still searching the answer.
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Old 01-19-2011
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Question ?pseudohypernatraemia

Hyperglycaemia causes pseudohyponatraemia, via osmotic dilution of plasma.
Maybe in the same way, hyperinsulinaemia leads to a drop in plasma [glucose]. This would in turn reduce the plasma osmolality (normally a function of [Na], [urea] and [glucose]).
By rearranging the equation, a reduced glucose, and a reduced osmolality would lead to a pseudohypernatraemia.

Just a thought
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The above post was thanked by:
dr z (01-19-2011)



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Endocrine-, Physiology-, Renal-

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