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  #1  
Old 01-31-2011
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Kidney Most common cause of nephrotic syndrome in adults?

There is a discrepancy between what Goljan & FA say (membranous GN) and what UW says (focal segmental glomerulosclerosis).
Would it be more correct to follow UW?
Thanks.
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Old 01-31-2011
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Default UW is correct

It used to be Membranous but recent studies are pointing to FSGS.

Look at this graph:

Most common cause of nephrotic syndrome in adults?-capture.jpg
click to enlarge

The left graph is for secondary causes and the right graph is for primary causes of NS, you can see that FSGS is the most common cause.

References:
http://pubget.com/paper/17699249
http://pubget.com/paper/17395661
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Old 01-31-2011
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Default

Quote:
Originally Posted by Hokolesqua View Post
It used to be Membranous but recent studies are pointing to FSGS.

Look at this graph:

Attachment 988
click to enlarge

The left graph is for secondary causes and the right graph is for primary causes of NS, you can see that FSGS is the most common cause.

References:
http://pubget.com/paper/17699249
http://pubget.com/paper/17395661
Super ... we got our answer !! Thanks.
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Old 08-29-2011
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Default Nephrotic Syndrome

what is the MCC of Nephrotic S. is adults?

Membranous or Focal Segmental???
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  #5  
Old 08-29-2011
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Default

Quote:
Originally Posted by bebix View Post
what is the MCC of Nephrotic S. is adults?

Membranous or Focal Segmental???
Focal Segmental
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  #6  
Old 08-29-2011
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Default membranous

membranous , according to kaplan
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  #7  
Old 08-29-2011
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Smile

Membranous, according to kaplan lectures.
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Old 08-29-2011
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Default

http://www.aafp.org/afp/2009/1115/p1129.html
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  #9  
Old 08-29-2011
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Focal is infact the most common as i can recall from Qbank Kaplan and the new edition ( Errata ) version of FA 2011 also says it FOCAL
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Old 02-02-2012
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Default Whats the most common cause of nephrotic syndrome in adults?

Kaplan and FA says membranous glomerulonephritis but ive come across 2 qbank questions (1 kaplan, 1 uworld) that say focal segmental glomerulonephritus is the most common cause of adult nephrotic syndrome.
The explanations said that it WAS membranous, but now the most common is focal segmental.

What do you guys think?
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Old 02-02-2012
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barone in his lecture said FOCAL SEGMENTAL is the new number 1
membranous is number 2

(he asked us to make that change in kaplan notes)
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  #12  
Old 02-05-2012
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Quote:
Originally Posted by mbbs2010 View Post
barone in his lecture said FOCAL SEGMENTAL is the new number 1
membranous is number 2

(he asked us to make that change in kaplan notes)

Thanks
I would have just went along with FA.
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Old 02-05-2012
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Default

Quote:
Originally Posted by Hokolesqua View Post
It used to be Membranous but recent studies are pointing to FSGS.

Look at this graph:

Attachment 988
click to enlarge

The left graph is for secondary causes and the right graph is for primary causes of NS, you can see that FSGS is the most common cause.

References:
http://pubget.com/paper/17699249
http://pubget.com/paper/17395661
Awesome job,
Thank you so much
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  #14  
Old 02-13-2012
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Default It was corrected

Don't know about Goljan yet, but I know it is corrected in FA in their 2011 errata to be the focal segmental.
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Old 03-14-2013
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Unhappy Focal Segmental....WHAT

Sorry to bump. I also thought the most common cause of Nephrotic Syndrome in adults was Membranous Glomerulonephritis, but it turns out to be Focal Segmental, that is clear.

Now my confusion is the following:
Focal Segmental...WHAT.

In my Kaplan lecture notes and First Aid notes I have Focal Segmental Glomerulosclerosis as a cause of nephrotic syndrome. But some of you guys type Focal Segmental Glomerulonephritis, and some Glomerulosclerosis..

The question arises since I took the Kaplan Diagnostic Exam and in the explanation of the question they say its Focal Segmental Glomerulonephritis. But i don't even have that diagnosis in my lecture notes.

Sorry to increase the confusion guys... But what is the difference between Focal Segmental Glomerulonephritis and Focal Segmental Glomerulosclerosis.
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  #16  
Old 04-07-2013
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Post Focal Segmental Glomerulosclerosis

Quote:
Originally Posted by medpack87 View Post
Sorry to bump. I also thought the most common cause of Nephrotic Syndrome in adults was Membranous Glomerulonephritis, but it turns out to be Focal Segmental, that is clear.

Now my confusion is the following:
Focal Segmental...WHAT.

In my Kaplan lecture notes and First Aid notes I have Focal Segmental Glomerulosclerosis as a cause of nephrotic syndrome. But some of you guys type Focal Segmental Glomerulonephritis, and some Glomerulosclerosis..

The question arises since I took the Kaplan Diagnostic Exam and in the explanation of the question they say its Focal Segmental Glomerulonephritis. But i don't even have that diagnosis in my lecture notes.

Sorry to increase the confusion guys... But what is the difference between Focal Segmental Glomerulonephritis and Focal Segmental Glomerulosclerosis.
Maybe its a Kaplan mistake, Focal Segmental Glomerulosclerosis is the most common cause of adult nephrotic syndrome and the second most common cause is Membranous glomerulonephritis.
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  #17  
Old 04-07-2013
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Pathoma says FSGS is most common in African Americans and Hispanics, while its Membranous for Caucasians.
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  #18  
Old 10-19-2015
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X Ray This is so bizarre!

I just solved a question in UW, QID 382 and it says that the most common cause of nephrotic in adults is membranous nephropathy. However goljan, pathoma, and internet says its FSGS, the reference they posted is from 2011. even UpToDate says its FSGS. What to do?
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