Test your knowledge! - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
Home
USMLE Articles
USMLE News
USMLE Polls
USMLE Books
USMLE Apps
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 02-06-2011
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 590
Threads: 31
Thanked 1,230 Times in 411 Posts
Reputation: 1254
Arrow Test your knowledge!

Hello all! This is the first thread I've actually started. So, my school has a Problem Based Learning curriculum, and part of what we do is make up board-style questions for our groups based on our readings. I thought I'd share the ones I've written here - an extra question never hurts, they aren't from any qbank so there are no spoilers, and it's kind of fun quizzing each other. Here's the first one:

A 43-year-old white male presents with jaundice of several days' duration. He reports mild fatigue and "all-over itchiness". His medical history is significant for ulcerative colitis, frequent headaches, and sleep apnea. ERCP confirms a diagnosis of primary sclerosing cholangitis. Typical antibody findings would include ANA, anti-smooth muscle, and:
  1. Anti-HepBc IgG
  2. Anti-glycoprotein 210 antibody
  3. Anti-topoisomerase antibody
  4. Atypical p-ANCA antibody
  5. Von Meyenburg complexes
Reply With Quote Quick reply to this message
The above post was thanked by:
13monument (02-06-2011), aktorque (02-06-2011), Amenah (02-06-2011), archit2608 (02-06-2011), bhagirath (04-12-2011), christusherbert (02-06-2011), dr z (02-06-2011), dr_ram (02-06-2011), drgabroomunda (02-13-2011), harlesmd (04-11-2011), mle guy (02-06-2011), rah_mem (04-12-2011), Sana Zahid (02-06-2011), StepTaker (02-06-2011), surez18 (05-15-2011)



  #2  
Old 02-06-2011
13monument's Avatar
USMLE Forums Addict
 
Steps History: Step 1 Only
Posts: 129
Threads: 3
Thanked 110 Times in 64 Posts
Reputation: 120
Default

This is really awesome man. The structure of the question is so well versed, it feels like a Kaplan or UW question.

I really advise you to think seriously about starting your own online qbank company

PS- my answer is p-ANCA
Reply With Quote Quick reply to this message
The above post was thanked by:
FrontalBossing (02-06-2011), harlesmd (04-11-2011), Mondoshawan (02-06-2011)
  #3  
Old 02-06-2011
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 590
Threads: 31
Thanked 1,230 Times in 411 Posts
Reputation: 1254
Default correct!

Answer: D. Atypical p-ANCA antibody.

Perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA) are found in up to 80% of PSC patients - they are atypical, according to Robbins, because they are directed against a nuclear envelope protein insted of myeloperoxidase; however, the histologic appearance is the same as other p-ANCAs.
  • p-ANCAs are also found in patients with Churg-Strauss syndrome (50%), microscopic polyangiitis (60%; rarely positive in polyarteritis nodosa now that PAN and MPA are classified as different diseases, but might still be associated on the boards), Kawasaki disease, glomerular basement membrane disease, rheumatoid arthritis (especially JRA), IBD (Crohn's and ulcerative colitis), and drug-induced vasculitis.
    • 75-90% of PSC patients have IBD
      • 87% of these ulcerative colitis
      • 13% with Crohn colitis
  • c-ANCA is associated with Wegener's granulomatosis
  • anti-HepBc IgG (A) are indicative of past Hepatitis B infection
  • anti-glycoprotein 210 (B) is found in primary biliary cirrhosis
  • anti-topoisomerase (C) is found in systemic scleroderma
  • Von Meyenburg complexes (E) are not immune complexes; rather, they are clinically non-significant fibrous clusters that can look like like liver metastases.
Reply With Quote Quick reply to this message
The above post was thanked by:
aktorque (02-06-2011), Amenah (02-06-2011), bhagirath (04-12-2011), bronchiole (04-13-2011), christusherbert (02-06-2011), Dr I 85 (02-06-2011), dr.husnain (04-11-2011), drmuh (02-06-2011), Eric Zhuang (04-12-2011), FrontalBossing (02-06-2011), harlesmd (04-11-2011), KUMS (02-08-2011), mle guy (02-06-2011), Sana Zahid (02-09-2011), srivar85 (08-07-2011), umeraulakh (01-20-2012), varunshetty00 (02-06-2011)
 
  #4  
Old 02-06-2011
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 590
Threads: 31
Thanked 1,230 Times in 411 Posts
Reputation: 1254
Default

Quote:
Originally Posted by 13monument View Post
This is really awesome man. The structure of the question is so well versed, it feels like a Kaplan or UW question. I really advise you to think seriously about starting your own online qbank company
PS- my answer is p-ANCA
Thanks for the compliment! I think I'll be pretty busy for the next several years, though!

I'll try to put up a question every day or two.
Reply With Quote Quick reply to this message
The above post was thanked by:
N Nur (02-10-2012)
  #5  
Old 02-06-2011
USMLE Forums Scout
 
Steps History: Not yet
Posts: 24
Threads: 4
Thanked 19 Times in 11 Posts
Reputation: 29
Default

Great question. Thanks! PLease post more of these
Reply With Quote Quick reply to this message
  #6  
Old 02-07-2011
manphnx's Avatar
USMLE Forums Scout
 
Steps History: Not yet
Posts: 12
Threads: 1
Thanked 19 Times in 6 Posts
Reputation: 29
Default a very gud question

Quote:
Originally Posted by Mondoshawan View Post
Thanks for the compliment! I think I'll be pretty busy for the next several years, though!

I'll try to put up a question every day or two.
that was a very good question. so is it like a thread where any body can post their questions? or its just u? cause i have a couple of questions myself...
by the way this is a gud start by u... keep it up
Reply With Quote Quick reply to this message
The above post was thanked by:
Mondoshawan (02-09-2011)
  #7  
Old 02-09-2011
USMLE Forums Master
 
Steps History: 1+CK+CS
Posts: 590
Threads: 31
Thanked 1,230 Times in 411 Posts
Reputation: 1254
Default

Quote:
Originally Posted by manphnx View Post
that was a very good question. so is it like a thread where any body can post their questions? or its just u? cause i have a couple of questions myself...
Put them up! It seems like people have been starting a new thread in the Step 1 Forum with each question rather than adding to the same thread. The admins are quite diligent about tagging posts, so don't worry about getting lost in the shuffle - we can always search for threads tagged "step-1-question"...
Reply With Quote Quick reply to this message
The above post was thanked by:
manphnx (02-12-2011)
  #8  
Old 02-12-2011
manphnx's Avatar
USMLE Forums Scout
 
Steps History: Not yet
Posts: 12
Threads: 1
Thanked 19 Times in 6 Posts
Reputation: 29
Default pathology

a 35 year old male with a history of jaundice for 15days. preceded by prodromal illness. his serum was positive for HBs ag. a clinical diagnosis of acute hepatitis is made. what is the next best confirmatory investigation?
a. Anti HBe ag antibody
b. Anti Hbe IgM antibody
c. HBV DNA by PCR
d. HBe antigen
Reply With Quote Quick reply to this message
  #9  
Old 04-11-2011
USMLE Forums Newbie
 
Steps History: Step 1 Only
Posts: 1
Threads: 0
Thanked 0 Times in 0 Posts
Reputation: 10
Default

i gues its hbv-dna by pcr.
Reply With Quote Quick reply to this message
  #10  
Old 04-12-2011
USMLE Forums Veteran
 
Steps History: Not yet
Posts: 236
Threads: 4
Thanked 124 Times in 96 Posts
Reputation: 134
Default

b. Anti Hbe IgM antibody
Reply With Quote Quick reply to this message
  #11  
Old 04-12-2011
USMLE Forums Scout
 
Steps History: Step 1 Only
Posts: 38
Threads: 16
Thanked 5 Times in 4 Posts
Reputation: 15
Default nice one

it B , cos he tell acute hepatitis
Reply With Quote Quick reply to this message
  #12  
Old 04-13-2011
Banned
 
Steps History: 1 + CK
Posts: 751
Threads: 133
Thanked 308 Times in 192 Posts
Reputation: 318
Default

Good question.
Reply With Quote Quick reply to this message
  #13  
Old 04-13-2011
USMLE Forums Veteran
 
Steps History: Not yet
Posts: 236
Threads: 4
Thanked 124 Times in 96 Posts
Reputation: 134
Default

so whats the answer ???
Reply With Quote Quick reply to this message
  #14  
Old 01-19-2012
USMLE Forums Newbie
 
Steps History: Not yet
Posts: 1
Threads: 0
Thanked 0 Times in 0 Posts
Reputation: 10
Default

Quote:
Originally Posted by manphnx View Post
a 35 year old male with a history of jaundice for 15days. preceded by prodromal illness. his serum was positive for HBs ag. a clinical diagnosis of acute hepatitis is made. what is the next best confirmatory investigation?
a. Anti HBe ag antibody
b. Anti Hbe IgM antibody
c. HBV DNA by PCR
d. HBe antigen
Ans: D

Anti-HBe Antibody is negative
Reply With Quote Quick reply to this message
  #15  
Old 01-20-2012
Hitman's Avatar
USMLE Forums Master
 
Steps History: Not yet
Posts: 928
Threads: 17
Thanked 539 Times in 375 Posts
Reputation: 549
Default

yes D .... Hbe Ag .......
Reply With Quote Quick reply to this message






Reply

Tags
Gastrointestinal-Tract-, Pathology-, Step-1-Questions

Quick Reply
Message:
Options

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Location
Where you live. Leave blank if you don't want to tell.

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.



Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes


Similar Threads
Thread Thread Starter Forum Replies Last Post
USMLE Step 2 Triage: An Effective No-nonsense Review of Clinical Knowledge Sabio USMLE Step 2 CK Forum 3 05-17-2011 09:27 AM
The difference between Anterior Drawer Test and Lachman Test rasheed USMLE Step 2 CK Bits & Pieces 1 04-09-2011 07:21 AM
Test Scheduling; Not sure i_m_possible ECFMG Forum 2 12-12-2010 07:33 PM
Ath.Pantelis ; How do you have such a great knowledge? Seetal USMLE Step 1 Forum 5 04-04-2010 09:53 AM
Initial Test is the Final Test? Hohepa USMLE Step 2 CK Forum 4 03-23-2010 11:49 AM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)