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  #1  
Old 02-11-2011
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Arrow Similar Qn tested on USMLE

Which one of the following transplacental infections is associated with sensorineural hearing loss, blindness and periventricular calcification?

A) Cytomegalovirus

B) Toxoplasmosis

C) Syphilis

D) Herpes genitalis

E) Rubella
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  #2  
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Think its CMV
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  #3  
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Arrow

Quote:
Originally Posted by ibukun View Post
Think its CMV
What makes you think its CMV? why not Rubella?
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  #4  
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All the signs points to TORCH complex. Toxoplasma gondii known to cause intraventricular calcification. Rubella - cataract and deafness CMV - hearing loss But I'll go with Toxoplasma bcoz of the classic traid consisting of chorioretinitis, intraventricular calcification and hydrocephalus... What is the correct ans..???
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  #5  
Old 02-11-2011
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Default B

i wud say toxoplasmosis.
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  #6  
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its majorly because of the periventricular calcification as well as the chorioretinitis though rubella causes deafness it rarely causes calcifications
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  #7  
Old 02-11-2011
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Default cmv

I would go with CMV as well. Aren't the calcifications diffuse in congenital toxoplasmosis?
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  #8  
Old 02-11-2011
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Help

CMV (periventricular),
Similar Qn tested on USMLE-ct002.jpg
click to enlarge

Toxo (diffuse)
Similar Qn tested on USMLE-ct001.jpg
click to enlarge
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  #9  
Old 02-11-2011
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Arrow A) Cytomegalovirus

A) Cytomegalovirus

Periventricular calcification is specific finding for CMV.
Similar Qn tested on USMLE-pvc.jpg
click image to enlarge

Rubella - sensorineural hearing loss
Similar Qn tested on USMLE-rubella.jpg
click image to enlarge

Syphilis - saddle nose deformity
Similar Qn tested on USMLE-saddle.jpg
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Toxoplasmosis - necrotizing retinochoroiditis
Similar Qn tested on USMLE-retinonec.jpg
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  #10  
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I had a question that was along the same lines as the one posted.

A newborn has multiple hemorrhagic cutaneous lesions and does respond to auditory stimuli. A CT scan of the head shows periventricular calcifications. Which of the following did the newborn's mother most likely develop during the first 16 weeks of gestations?

A) A 3-day rash
B) Generalized lymphadenopathy
C) Painless genital ulcers
D) Transient arthralgia
E) Vesicular genital lesions
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  #11  
Old 02-12-2011
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Arrow

Quote:
Originally Posted by FrontalBossing View Post
I had a question that was along the same lines as the one posted.

A newborn has multiple hemorrhagic cutaneous lesions and does respond to auditory stimuli. A CT scan of the head shows periventricular calcifications. Which of the following did the newborn's mother most likely develop during the first 16 weeks of gestations?

A) A 3-day rash
B) Generalized lymphadenopathy
C) Painless genital ulcers
D) Transient arthralgia
E) Vesicular genital lesions

Where did you get this qn? looks very tough!!

I'll go with A) A 3-day rash
Coz, CMV resemble signs of rubella in rare cases.
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  #12  
Old 02-12-2011
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Default B

CMV has Sx similar to Mononucleiosis. So I'd go with Generalized Lymphadenopathy.
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  #13  
Old 02-12-2011
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I think I'd choose "B. Generalized lymphadenopathy" as well - the innocuous "flu-like symptoms" that seem to go with everything. I didn't know about it sometimes presenting like rubella, though, I'll have to remember that...
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  #14  
Old 02-12-2011
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Arrow B) Generalized lymphadenopathy

Yes, Mondoshawan and usmle0987 are absolutely right. CMV can cause Generalized lymphadenopathy.

I agee with you guys.
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  #15  
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Sorry for the late reply, but the correct answer is indeed B.) generalized lymphadenopathy.

This is a kaplan question, here is the explanation.

The triad of cutaneous hemorrhages "blueberry muffin baby", deafness, and periventricular CNS calcifications suggests congenital CMV infection, the most common cause of intrauterine fetal viral infection.
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  #16  
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Quote:
Originally Posted by aktorque View Post
Where did you get this qn? looks very tough!!

I'll go with A) A 3-day rash
Coz, CMV resemble signs of rubella in rare cases.
I got it from Kaplan qbank, i also went with 3-day rash. I posted the answer explanation though, I hope it helps.
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  #17  
Old 02-12-2011
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Arrow blueberry muffin baby

Quote:
Originally Posted by FrontalBossing View Post
Sorry for the late reply, but the correct answer is indeed B.) generalized lymphadenopathy.

This is a kaplan question, here is the explanation.

The triad of cutaneous hemorrhages "blueberry muffin baby", deafness, and periventricular CNS calcifications suggests congenital CMV infection, the most common cause of intrauterine fetal viral infection.
Similar Qn tested on USMLE-babyskin.jpg
click image to enlarge
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