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Old 03-01-2011
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Question Role of Plasmin on complement?

Can someone please explain this?
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Old 03-01-2011
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I know of two effects:
  • plasmin cleaves C2b into kinin
  • I think plasmin can activate C3
Anyone else know of any? It seems like all those serine proteases are sort of promiscous, and it seems hard to keep track of who can do what to whom...
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Old 03-02-2011
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Plasmin also cleaves C5 to C5a.. (major chemo attractant for neutrophils)
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