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Old 04-15-2014
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Star Prolactin and Pregnancy

I don't know if this is right.....please correct if I'm wrong.....

1.Estrogen increases synthesis of prolactin in the anterior pituitary.
BUT.......it prevents its release.....

2.As a result, the pituitary doubles in size during pregnancy and prolactin levels during pregnancy are low.

3.All the prolactin that has been synthesized and stored, is released after pregnancy, when estrogen levels start to fall.

4.So thereafter, post-pregnancy, prolactin maintains lactation.....
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Old 04-15-2014
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Anyone????

I really don't don't understand the relationship between Prolactin and Estrogen before and after pregnancy.................
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Old 04-15-2014
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The hormones prolactin and estrogen oppose each other.. in normal condition high levels of estrogen suppress prolactin.. in the postpartum women after the delivery of baby and placenta. Placenta is source of high hormones level in pregnancy.. ovaries are quiet because FSH that turns them on is absent.. as she enters this low estrogen state sensitivity of prolactin release is turned on. If she breastfed frequently enough FSH signal will be suppressed and estrogen will stay low. She will not menstruate and she will produce copious amounts of milk. When breast feeding and nipple stimulation stops FSH suppression is not complete.. and she begins her menstruation and becomes fertile again. When FSH signal becomes strong estrogen level will rise and prolactin decreases again. I hope this helps...
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Originally Posted by medstud. View Post
I don't know if this is right.....please correct if I'm wrong.....

1.Estrogen increases synthesis of prolactin in the anterior pituitary.
BUT.......it prevents its release.....

2.As a result, the pituitary doubles in size during pregnancy and prolactin levels during pregnancy are low.

3.All the prolactin that has been synthesized and stored, is released after pregnancy, when estrogen levels start to fall.

4.So thereafter, post-pregnancy, prolactin maintains lactation.....
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