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  #1  
Old 04-15-2014
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Default Really Challenging Question!!!

Q) A 27 year old MMA fighter had 10 egg whites, grilled chicken and a glass of Whey protein isolate shake. Which of the following would most likely be observed in his postprandial blood profile?

A. Increased Insulin, Decreased Glucagon, Decreased GIP
B. Increased Insulin, Decreased Glucagon, Increased GIP
C. Increased Insulin, Increased Glucagon, Decreased GIP
D. Increased Insulin, Increased Glucagon, Increased GIP
E. Decreased Insulin, Decreased Glucagon, Decreased GIP
F. Decreased Insulin, Increased Glucagon, Decreased GIP
G. Decreased Insulin, Decreased Glucagon, Increased GIP
H. Decreased Insulin, Increased Glucagon, Increased GIP

Its pretty confusing, so think carefully.......

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i think its D
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Old 04-15-2014
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Quote:
Originally Posted by medstud. View Post
Q) A 27 year old MMA fighter had 10 egg whites, grilled chicken and a glass of Whey protein isolate shake. Which of the following would most likely be observed in his postprandial blood profile?

A. Increased Insulin, Decreased Glucagon, Decreased GIP
B. Increased Insulin, Decreased Glucagon, Increased GIP
C. Increased Insulin, Increased Glucagon, Decreased GIP
D. Increased Insulin, Increased Glucagon, Increased GIP
E. Decreased Insulin, Decreased Glucagon, Decreased GIP
F. Decreased Insulin, Increased Glucagon, Decreased GIP
G. Decreased Insulin, Decreased Glucagon, Increased GIP
H. Decreased Insulin, Increased Glucagon, Increased GIP

Its pretty confusing, so think carefully.......

P.S.-I wrote this Question
i think is B.
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Old 04-15-2014
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I think it's B

There's a similar question in Kaplan Qbank and I think Dr. Fischer briefly mentions it in the GI lectures!



Looking forward to the real answer.

Last edited by dwijeshsheth; 04-15-2014 at 07:58 PM. Reason: typo
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Old 04-15-2014
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I think its B too..
Quote:
Originally Posted by medstud. View Post
Q) A 27 year old MMA fighter had 10 egg whites, grilled chicken and a glass of Whey protein isolate shake. Which of the following would most likely be observed in his postprandial blood profile?

A. Increased Insulin, Decreased Glucagon, Decreased GIP
B. Increased Insulin, Decreased Glucagon, Increased GIP
C. Increased Insulin, Increased Glucagon, Decreased GIP
D. Increased Insulin, Increased Glucagon, Increased GIP
E. Decreased Insulin, Decreased Glucagon, Decreased GIP
F. Decreased Insulin, Increased Glucagon, Decreased GIP
G. Decreased Insulin, Decreased Glucagon, Increased GIP
H. Decreased Insulin, Increased Glucagon, Increased GIP

Its pretty confusing, so think carefully.......

P.S.-I wrote this Question
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Old 04-15-2014
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the Answer should be D ... whole protein diet ... no carbohydrates , so glucose will be less and that would stimulate glucagon synthesis ...also Amino acids will stimulate GIP that would increase Insulin secretion
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Old 04-16-2014
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Yes. Its D.
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Old 04-16-2014
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Quote:
Originally Posted by medstud. View Post
Yes. Its D.
i thought insulin and glucagon ALWAYS opposed each other...
guess i was wrong.
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Old 04-16-2014
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Quote:
Originally Posted by medstud. View Post
Yes. Its D.
could you do a detailed explaination please
very good question indeed.
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Old 04-16-2014
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He had a High Protein meal.

*GIP is elevated in response to carbs, fats and protein.

*Regarding Insulin...........Amino acids have an equally same effect on Insulin rise as glucose does. So there would be a large rise in Insulin to handle the large rise in amino acids( Insulin would be responsible for building muscle by utilizing these AA's, cause it has an ANABOLIC action)

BUT......there is little, if not no carbs in this meal...so consequently there would be hypoglycemia due to Insulin......

*So counter act this hypoglycemia, Glucagon levels rise.
(Glucagon would then increase gluconeogenesis to elevate blood glucose)

Q. How do Glucagon levels rise ???

A. By two mechanisms....

1) In response to a high protein meal, CCK is released (remember CCK release is stimulated by both fats and proteins). This CCK "alerts" Alpha cells to an incoming rush of amino acids into the bloodstream, thereby increasing Glucagon secretion.

2) Amino acids, especially ARGININE, directly stimulate Glucagon release.

Hopes this helps......
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Old 04-16-2014
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Good ass question!
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