A pregnant female did ultrasound and it was reported as the baby is having a fluid sac on the lower back. What medication could exacerbate the dietary deficiency responsible for the this defect?
I think it is NTD caused by folate deficiency..
From interfering the dietary folate absorption and associated with NTD , most likely the drug will be anticonvulsant...
So i chose valproic acid as it is a teratogenic anticonvulsant causing NTD
valpraoic acid and phenytoin inhibit the intestinal conjugases which are responisble for folic acid absorption
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