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Old 03-13-2011
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Neuro Why respiratory depression in increased ICP?

how does an increase in Intracranial pressure causes respiratory depression?
thanxx
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Old 03-13-2011
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Idea!

Quote:
Originally Posted by Rawalian View Post
how does an increase in Intracranial pressure causes respiratory depression?
thanxx


This is what I understand.....raised ICP is due to diffuse axonal injury or hge or sol....so,this ICP at one point is more than arterial pressure . blood supply to the brain is compromised.

then,central chemo receptor senses lower ph and increases sympathetic drive resulting increased TPR and CO(by increasing contractility). hence, HTN.

Baroreceptor on carotid a. senses increased BP, so, para sym causes bradycardia. also, raised ICP stimulates vagus.


Resp depression is due to compression of brain stem(medulla) due to raised ICP.


here, the key point is both sym and para sym is stimulated.
sym has better control on vessel------HTN
para sym better control on heart-------bradycardia


I hope it helped.
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Old 03-13-2011
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thanx... yes it helped besides the main point bothering me was respiratory depression...
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Old 03-13-2011
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Quote:
Originally Posted by Rawalian View Post
thanx... yes it helped besides the main point bothering me was respiratory depression...


welcome...
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