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  #1  
Old 04-04-2011
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Question The mother of TGA baby!

An infant present a transposition of a great vessels. which of the following symptoms is this infant's mother most likely experiencing

1- arachnodactyly, hyperextensible joints and aortic aneurysm
2- cold intolerance, delayed reflexes, constipation
3- megaloblastic anemia without neurologic symptoms
4- mild fever with descending maculopapular rash and clear buccal mucosa
5- polydipsia; polyuria and blurred vision
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Old 04-04-2011
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I'd say option number 4.
The mother had rubella and the baby got TGA.
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Originally Posted by Chessmatic View Post
I'd say option number 4.
The mother had rubella and the baby got TGA.
no, There is no risk of transposition of great vessel in Rubella.
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Old 04-04-2011
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Quote:
Originally Posted by tinhi View Post
no, There is no risk of transposition of great vessel in Rubella.
Risk factors
By Mayo Clinic staff
Although the exact cause of transposition of the great arteries is unknown, several factors may increase the risk of a baby being born with this condition, including:

A history of German measles (rubella) or another viral illness in the mother during pregnancy
A family history of transposition of the great arteries or another congenital heart defect
Poor nutrition during pregnancy
Excessive alcohol consumption during pregnancy
A mother older than age 40
A mother who has poorly controlled diabetes
Down syndrome in the baby
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Old 04-04-2011
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Quote:
Originally Posted by Chessmatic View Post
I'd say option number 4.
The mother had rubella and the baby got TGA.
R u sure!!!!!!? when did you take your step 1!!

Transposition of the great vessels :

Etiology (most common)- Gestational diabetes mellitus of an expectant mother is a risk factor that has been described for the fetus having TGV.

Additionally, the children of diabetic mothers are more likely to have aortic coarctation.

The correct ans is polydipsia, polyuria and blurred vision
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Old 04-04-2011
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Originally Posted by aktorque View Post
R u sure!!!!!!? when did you take your step 1!!

Transposition of the great vessels :

Etiology - Gestational diabetes mellitus of an expectant mother is a risk factor that has been described for the fetus having TGV.

Additionally, the children of diabetic mothers are more likely to have aortic coarctation.

The correct ans is polydipsia, polyuria and blurred vision
Bravo !! The answer is diabetes
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  #7  
Old 04-04-2011
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Originally Posted by tinhi View Post
no, There is no risk of transposition of great vessel in Rubella.
Exactly, this is what I first thought of when I first saw Rubella. CMV didn't fit either, nor did any other TORCH infections.

Althought Rubella can cause CHD (patent DA), its not the same as TGA.

But I learned something new today, that DM causes birth defects! Thanks OP

But I dont understand why there is blurred vision... I hope they dont mean diabetic retinopathy.. which would result because of years worth of uncontrolled BG levels..
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Old 04-04-2011
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Originally Posted by patelMD View Post
Exactly, this is what I first thought of when I first saw Rubella. CMV didn't fit either, nor did any other TORCH infections.

Althought Rubella can cause CHD (patent DA), its not the same as TGA.

But I learned something new today, that DM causes birth defects! Thanks OP

But I dont understand why there is blurred vision... I hope they dont mean diabetic retinopathy.. which would result because of years worth of uncontrolled BG levels..
the cause of the blurred vision is high blood sugar. The high blood sugar pulls fluid from the lenses of the eyes affecting focus, it's a clue that her diabetes is not well controlled, so there is a risk of transposition of great vessel, and ( caudal regression, anal atresia .. etc)
otherwise I don't think that a mother's well controlled diabetes will lead to infant's complications
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Originally Posted by tinhi View Post
the cause of the blurred vision is high blood sugar. The high blood sugar pulls fluid from the lenses of the eyes affecting focus, it's a clue that her diabetes is not well controlled, so there is a risk of transposition of great vessel, and ( caudal regression, anal atresia .. etc)
otherwise I don't think that a mother's well controlled diabetes will lead to infant's complications
Makes sense, thanks!
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Old 04-04-2011
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Quote:
Originally Posted by patelMD View Post
Makes sense, thanks!
you're welcome
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