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Old 04-06-2011
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Pancreas The highest risk factor for predisposing pancreatic cancer?

Hi there,
Which of the both is the highest risk factor predisposing to pancreatic cancer, smoking or alcoholic consumption? Anyone can answer this.

I knew that smoking is the most important environmental risk factor for pancreatic cancer. However, alcohol abuse can cause acute pancreatitis or chronic pancreatitis. It doubles the risk with smoking plus alcohol. Some research group shows the risk of the pancreatic cancer is higher after 20 years of chronic pancreatitis. I 'm confused now. What is the best choice for this question? I appreciate it!
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Old 04-06-2011
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According to some of the latest research:

In multiple cohort and case-control studies, the relative risk for developing pancreatic cancer among smokers was at least 1.5

Data regarding the impact of coffee and alcohol ingestion on the risk of pancreatic cancer are conflicting. For both of these factors, a few studies have suggested an increased risk, but the majority of published series in the last 15 years have failed to convincingly demonstrate such a relationship. The relationship between alcohol use and pancreatic cancer is confounded by cigarette smoking.

So go with Smoking!
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Old 04-06-2011
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Thanks for your quick answer. It's helpful.
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