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Old 04-12-2011
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Arrow From NBME sample question; Need answer

A neonate is born with ambiguous genitalia. The clitoris is enlarged, there is a single perineal opening anterior to the anus, and no masses are palpable in the labioscrotal pouches or the inguinal canal. Which of the following is the most likely cause of the sexual ambiguity in this neonate ?
A. Androgen-insensitivity syndrome
B. 21-hydroxylase deficiency
C. Mixed gonadal dysgenesis
D. 5 alpha reductase deficiency
E. True hermaphroditism
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  #2  
Old 04-12-2011
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21 hydroxylase deficiency
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Old 11-02-2011
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I agree the answer is 21-hydroxylase deficiency
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Old 11-02-2011
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how can u explain the single opening anterior to the anus.....??
is it the vagina or the urethra??

Last edited by heman466s; 11-02-2011 at 12:21 PM.
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Old 11-02-2011
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B. 21-hydroxylase deficiency
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