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Old 05-19-2014
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Jackie, a seven year old on holiday in Jamaica, was brought to the emergency room because she had had a convulsion in the early evening after an all-day hike with friends. Her skin was cold and clammy. Her parents said that she liked to try new foods (she had done so at lunch) and that she had never had a convulsion before. You suspect that she is suffering from hypoglycemia. A blood sample is taken before treatment with glucose confirmed the diagnosis of hypoglycemia (the level of glucose was 2 mmol/l, or 36 mg/dl). When special assays were done on her blood the level of fatty acids was high and the level of ketoacids was very low. What caused Jackie’s hypoglycemia? Why did the hypoglycemia occur so long (6 hours ) after her last meal?
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Old 05-19-2014
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Quote:
Originally Posted by biochemist View Post
Jackie, a seven year old on holiday in Jamaica, was brought to the emergency room because she had had a convulsion in the early evening after an all-day hike with friends. Her skin was cold and clammy. Her parents said that she liked to try new foods (she had done so at lunch) and that she had never had a convulsion before. You suspect that she is suffering from hypoglycemia. A blood sample is taken before treatment with glucose confirmed the diagnosis of hypoglycemia (the level of glucose was 2 mmol/l, or 36 mg/dl). When special assays were done on her blood the level of fatty acids was high and the level of ketoacids was very low. What caused Jackie’s hypoglycemia? Why did the hypoglycemia occur so long (6 hours ) after her last meal?

carnitine deficency...
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Old 05-19-2014
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but what caused the hypoglycemia to be late?
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Old 05-19-2014
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Originally Posted by biochemist View Post
but what caused the hypoglycemia to be late?
cause she will first rely on glycogenolysis and gluconeogenesis, once glycogenolysis is over (stretching at the most lasts 12-18h in starvation state) gluconeogenesis becomes prevalent and as we know is very high energy consuming so it will need beta oxidation as its "fuel", no carnitine ----> no nadh fadh2 to produce ATP ----> no fuel for gluconeogenesis---> hypoglycemia

correct me if im wrong please
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