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Old 04-15-2011
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Question How many ATPs

Hello, hope someone can clear this up for me.
FA 2010 p.97...under...Glycolysis/ATP production: Aerobic metabolism of glucose produces 32 ATP via malate-aspartate shuttle or 30 ATP via glycerol-3-phosphate. I have looked at Kaplan LN and it says 36-38 (depending on the shuttle used)......but anyway, why the big number difference? What am i missing here? Thanks for your reply.
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Old 04-15-2011
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First Aid counts ATP as follows:
Glucose --> 2pyrovate: yielding 2 ATP and 2 NADH
these 2 NADH will produce 6 ATP if utilized through the malate-asp. shuttle.

2actyl CoA via Kreb's cycle will yield 24 ATP
so total production = 2+6+24 = 32 ATP

but they're missing the conversion of 2pyrovate to 2acetyl CoA which will yield 2NADH = 6 ATP which is then added to 32 to yield 38ATP as calculated in kaplan's notes
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Old 04-15-2011
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Also have a look at these two threads:
How many ATPs per Glucose Molecule
32 ATPs per glucose molecule?
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Old 04-16-2011
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Thanks very much carisma_200x and Rasheed..
I noticed soon after posting that this q had already been asked in the forum.. Great help!

Quote:
Originally Posted by carisma_200x View Post
First Aid counts ATP as follows:
Glucose --> 2pyrovate: yielding 2 ATP and 2 NADH
these 2 NADH will produce 6 ATP if utilized through the malate-asp. shuttle.

2actyl CoA via Kreb's cycle will yield 24 ATP
so total production = 2+6+24 = 32 ATP

but they're missing the conversion of 2pyrovate to 2acetyl CoA which will yield 2NADH = 6 ATP which is then added to 32 to yield 38ATP as calculated in kaplan's notes
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