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  #1  
Old 11-14-2009
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Microscope Intestinal Micrograph USMLE Question

A micrograph of the colon of a 23 year old healthy individual is shown;

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Intestinal Micrograph USMLE Question-intestine.jpg
copyright: Wikimedia commons

The pigment seen is
a- lipofuscin
b- hemosiderin
c- melanin
d- hyaline
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Old 11-15-2009
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hemosiderin!
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Old 11-15-2009
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hemosiderin
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Old 11-15-2009
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Default Melanosis Coli

The clue to the answer is that the patient is "healthy".
This is melanosis coli. The pigment is not melanin (common mistake), it's lipofuscin which gets accumulated in melanosis coli.
Melanosis coli has no clinical significance as it can be seen in normal people and the only association in some cases is with laxative abuse.
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Old 11-21-2009
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This is just another proof that's it's impossible to differentiate melanin from hemosiderin from lipofuscin from the microscope only, they must give some clues in the history
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Old 11-22-2009
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Default intestinal micrograpf USMLE question.

There are good pathology pictues of Melanosis Coli in the Pathoogy library .
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Old 11-22-2009
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Quote:
Originally Posted by Laurentiu View Post
There are good pathology pictues of Melanosis Coli in the Pathoogy library .
Which pathology library? Is it an online library? Can you send us the link
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Old 11-22-2009
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Default Melanosis Coli

The address is :www.thetelepathology.com/cases/
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Gastrointestinal-Tract-, Histology-, Micrographs-, Pathology-, Step-1-Questions

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