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Old 04-28-2011
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DNA How high yield are oncogene associations etc?

I am just wondering if we need to memorize the different genetic associations of various cancers, for example that p53 is on chomosome 17p and associated with Li-Fraumeni syndrome, DPC on 18q is associated with colon cancer, etc. There are a bunch of these in FA, I am wondering if I need to get started on some hardcore memorization
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Old 04-28-2011
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I don't think you need to know everything from FA (STOP MEMORIZING). I suggest you to follow the UW. They got the exact usmle type of qns. UW follows the NBME and use the same scope of information that you really need to know for your exam. Don't study beyond the limit. You will get exhausted and its worthless.
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Old 04-28-2011
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Knowing the increasing genetic questions and clinical significance of these oncogenes, I would try to remember all from FA and UW/NMBE
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Old 04-28-2011
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Quote:
Originally Posted by aktorque View Post
I don't think you need to know everything from FA (STOP MEMORIZING). I suggest you to follow the UW. They got the exact usmle type of qns. UW follows the NBME and use the same scope of information that you really need to know for your exam. Don't study beyond the limit. You will get exhausted and its worthless.
I don't think it's possible to do well without memorizing some things! I think if you have a solid understanding of the material it's possible to pass. However, some things just have to be memorized. For example, a lot of microbiology and pharmacology is straigh-up memorizing; knowing how a drug works in a particular system requires understanding, but then you have to memorize the names of those drugs!
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Old 04-28-2011
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I agree It is high yield

The list of oncogenes is very very high yield, including the chromosomal locations of each one of them.

Have a look here also
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Old 08-13-2011
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Quote:
Originally Posted by heights View Post
I am just wondering if we need to memorize the different genetic associations of various cancers, for example that p53 is on chomosome 17p and associated with Li-Fraumeni syndrome, DPC on 18q is associated with colon cancer, etc. There are a bunch of these in FA, I am wondering if I need to get started on some hardcore memorization
@heights...do you still think we need to memorize all this?
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