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Old 11-17-2009
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Kidney Cells that secrete erythropoietin

It's confusing for me to determine which cells secrete erythropoietin?
Kaplan Lecture Note of histology says it is secreted by mesangial cells, however UW says it is secreted by peritubular capillary cells.
Any one who knows the exact answer is requested to answer it along with the source they are referencing from.
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Old 11-17-2009
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It's the peritubular capillaries

sources
http://en.wikipedia.org/wiki/Erythropoietin
http://www.ncbi.nlm.nih.gov/pmc/arti...eport=abstract

Once again UW is better than Kaplan
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Old 11-17-2009
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hi there

me again. both the books are right! the mesangial cells are located at the peritubular. try looking for interesting pictures online. u can see how when the mesangial cells swell up, it causes a blockage of the tubules and the GFR decreases. u need a clear cartoon image to picture this easy.
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Old 12-20-2009
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There's another question in UW that says it's secreted from the renal cortex! that UW question is exactly question ID 1942
check it out
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Old 12-20-2009
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Idea!

Quote:
Originally Posted by Firas View Post
There's another question in UW that says it's secreted from the renal cortex! that UW question is exactly question ID 1942
check it out
This is not against what's said above. I think peritubular capillaries might be in the cortex.
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Old 12-27-2012
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Default EPO

Quote:
Originally Posted by Dr. N Elham View Post
It's confusing for me to determine which cells secrete erythropoietin?
Kaplan Lecture Note of histology says it is secreted by mesangial cells, however UW says it is secreted by peritubular capillary cells.
Any one who knows the exact answer is requested to answer it along with the source they are referencing from.
It's the interstitial cells of peritubular capillaries
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Histology-, Physiology-, Renal-

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