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Old 06-10-2014
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Default Is this a hairy cell or do I need to change my glasses?

I came across this question in UWorld. I answered it "Hairy cell leukemia" as I noticed a hairy cell in this blood smear (red arrow). The answer turned out to be "AML" as there is an Auer rod (blue arrow). I understand that with the presence of Auer rods it's going to be AML, but what about that hairy cell over there? or isn't this really a hairy cell?
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Old 06-10-2014
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that is not a hairy cell, they look really different for me;aulast=Galani
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gigisoe (06-10-2014)
Old 06-11-2014
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Sorry, for some reason I cannot see your pic. But anyway, I am a hematologist and the way to tell one from another is mainly on the chromatin of the nucleus. If it's thin it is probably acute leukemia but if it's condensed it's something more chronic as for example CLL. Also in Hairy cell leukemia you don't see any auer rod because it's a mature B Cell neoplasm.
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