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Old 05-04-2011
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Liver Mallory Body vs Councilman Body

Can anyone explain the difference between a Mallory body seen in alcoholic liver disease and a Councilman body seen in Viral hepatitis. I know both are eosinophilic, but I cannot understand the difference.

Also, does anyone have any good images of these two to compare?

Thanks!
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Old 05-04-2011
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Quote:
Originally Posted by apx85 View Post
Can anyone explain the difference between a Mallory body seen in alcoholic liver disease and a Councilman body seen in Viral hepatitis. I know both are eosinophilic, but I cannot understand the difference.

Also, does anyone have any good images of these two to compare?

Thanks!
Not exactly sure, but when I wiki'd it, they show two pictures that look different but then again in both, it says that the hepatocytes undergo apoptosis (Ballooning degeneration). May be the pictures will help -
http://en.wikipedia.org/wiki/Mallory_body
http://en.wikipedia.org/wiki/Councilman_body
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Old 05-05-2011
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well mallory bodies re intracytoplasmic structure these re damaged cytokeratin filaments n these re seen within cell as eosinphilic structures
councillman bodies re hepatocytes tht ve undergone apoptosis means among cell with ballooning degeneration u will certain eosinophilic shrunken hepatocytes
i hope it may help
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Old 05-05-2011
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Originally Posted by qurat21 View Post
well mallory bodies re intracytoplasmic structure these re damaged cytokeratin filaments n these re seen within cell as eosinphilic structures
councillman bodies re hepatocytes tht ve undergone apoptosis means among cell with ballooning degeneration u will certain eosinophilic shrunken hepatocytes
i hope it may help
Thanks guys!
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Old 08-16-2011
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Also, the main difference of those are about intracytoplasmic structure (Mallory Bodies) compared with extracytoplasmic structure(Councilman Bodies) USMLE Step 1 High Yield question.
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Old 08-16-2011
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this page also has good slides including Counsilman and Mallory bodies.
http://www6.ufrgs.br/favet/imunovet/...egressive.html
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