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  #1  
Old 05-07-2011
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Lungs Transudate vs Exudate

Heey guys hope you doing great ,, i need someone explains to me the distinction between the transudate and exudate and their major causes in the setting of the Pleural Effusion...
Big thanx in advance
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Old 05-07-2011
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Transudate occurs in the setting of increased hydrostatic pressure or decreased oncotic pressure for eg nephrotic syndrome, cirrhosis of the liver, congestive heart failure or hypothyroidism

Exudate occurs in the setting of inflammation (malignancy, infections etc)
for e.g. lung cancer, TB, pneumonia, bronchiectasis, pulmonary embolism
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Old 05-07-2011
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I never understood why pulmonary embolism causes exudative effusion. Isn't the effusion because the pressure in the vessel becomes too high after becoming blocked. Wouldn't that cause transudative effusion??
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Old 05-07-2011
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Default i think this could help you cause i have the same contradiction

The mechanism for the exudative pleural effusion is probably related to increased permeability of the capillaries in the lung, which results from the release of cytokines or inflammatory mediators (e.g. vascular endothelial growth factor) from the platelet-rich thrombi. The excessive interstitial lung fluid traverses the visceral pleura and accumulates into the pleural space.

http://www.medscape.com/viewarticle/583793
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Old 05-07-2011
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Quote:
Originally Posted by add1 View Post
Transudate occurs in the setting of increased hydrostatic pressure or decreased oncotic pressure for eg nephrotic syndrome, cirrhosis of the liver, congestive heart failure or hypothyroidism

Exudate occurs in the setting of inflammation (malignancy, infections etc)
for e.g. lung cancer, TB, pneumonia, bronchiectasis, pulmonary embolism
thanx now it looks better
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