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Old 05-11-2011
dr.dhruvdesai's Avatar
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Question Treatment for BLASTOMYCOSIS?

what is the preffered treatmeant for blastomycosis?

UW says Itraconazole..

FA says Itraconazole for local....and amphotericin B for general for blasto/histoplasma/coccidioidomycosis/paracoccidioidomycosis..

wats the corrects answer guys?
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Old 05-11-2011
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Important points to note before treating any patient with blastomycosis (or other known causes of systemic mycoses):

->Tx should be based on the nature, severity of disease
->Patients' ability to tolerate drug
->The toxicity of the drug

DOCs for mild blastomycosis is a prolonged course of oral itraconazole, whereas amphotericin B is used in patients with more severe (disseminated) disease or patients in whom itraconazole is contraindicated.

Ampotericin B is known for its several side effects (including fever, chills, renal toxicity etc), so should be used with caution.
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