Imprinting and X-Inactivation - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
USMLE Articles
Go Back   USMLE Forums > USMLE Step 1 Forum

USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam

Thread Tools Search this Thread Display Modes
Old 05-15-2011
USMLE Forums Guru
Steps History: Step 1 Only
Posts: 343
Threads: 127
Thanked 525 Times in 192 Posts
Reputation: 535
DNA Imprinting and X-Inactivation

Can someone explain difference between IMPRINTING and x-INACTIVATION?
It's kinda confusing
Reply With Quote Quick reply to this message

Old 05-15-2011
Hope2Pass's Avatar
USMLE Forums Master
Steps History: 1+CK+CS+3
Posts: 1,684
Threads: 213
Thanked 1,600 Times in 660 Posts
Reputation: 1610

Imprinting refers to the fact that a small number of genes are transcriptionally active only when transmitted by one of the two sexes. For imprinted loci, it is normal to have only the maternal active or only the paternal active.

So basically, u can have a loci of maternally active genes and at the same time u can have a different loci of paternally active genes.

Turning off the gene is Imprinting. It occurs at specific loci on several chromosomes and involved methylation and other mechanisms.

X Inactivation means inactivating the X chromosome to equalize the number of or amount of protein coded. Since X chromosomes can encode for 100's of proteins, X inactivation makes sure they dont go overboard! X inactivation occurs in the FEMALE embryo and is random, fixed and incomplete. All but one X chromosome is inactivated is called the Barr Body.

Does that solve anything?
Just think of this way - X Inactivation - for X chromosom, Imprinting - for all other genes.
Reply With Quote Quick reply to this message
The above post was thanked by:
7802 (05-16-2011), bushratehreem (03-27-2015), drpisho (04-25-2014), INCOGNITO (05-15-2011), Taiwan_Guy (05-16-2011)



Quick Reply

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Please enter a password for your user account. Note that passwords are case-sensitive.
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Where you live. Leave blank if you don't want to tell.


Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Genomic Imprinting apx85 USMLE Step 1 Forum 1 05-08-2011 05:10 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)