Calculating Allele Frequency from Genotype Frequencies? - USMLE Forums
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Old 05-16-2011
INCOGNITO's Avatar
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Genetics Calculating Allele Frequency from Genotype Frequencies?

A population has been assayed for a four-allele polymorphism, and the following genotype counts have been obtained..


Genotype Count
--------------------------------------------------------------------
1,1 = 4
1,3 = 8
1,4 = 3
2,3 = 5
2,4 = 9
3,3 = 4
3,4 = 6
4,4 = 11

On the basis of these genotype counts what are gene frequencies of alleles 1 , 2


A) 0.38, 0.28
B) 0.19, 0.14
c) 0.095, 0.07
d) 0.38, 0.20
e)

i am sure answer is not option e
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Old 05-16-2011
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I think is B)
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Old 05-16-2011
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ya u are right
what about gene frequency of allele 4
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Old 05-22-2011
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Quote:
Originally Posted by bebix View Post
I think is B)

can you explain the answer please... i dun get it
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Old 05-22-2011
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Quote:
Originally Posted by star123 View Post
can you explain the answer please... i dun get it
Genotype Count
--------------------------------------------------------------------
1,1 = 4
1,3 = 8
1,4 = 3
2,3 = 5
2,4 = 9
3,3 = 4
3,4 = 6
4,4 = 11

frequencies of allele 1
count the number of "1"
row 1 = 4 + 4
row 2 = 8
row 3 = 3
= 19

divided by the total =
(4+8+3+5+9+4+6+11)*2 = 100

19 / 100 = 0.19

frequencies of allele 2
5 + 9 = 14
14 / 100 = 0.14
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Old 05-23-2011
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similarly as i asked what is gene frequency of allele 4

3+9+6+22= 40
40/100=0.4

plz correct me if i m wrong

Last edited by INCOGNITO; 05-23-2011 at 04:29 PM.
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Old 05-23-2011
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why 200?

I think the correct answer is:

allele 4
40/100
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Old 05-23-2011
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Quote:
Originally Posted by bebix View Post
why 200?

I think the correct answer is:

allele 4
40/100
ya u are right
i corrected ma last post
answer is 40/100= 0.4
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