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USMLE Step 1 Forum USMLE Step 1 Discussion Forum: Let's talk about anything related to USMLE Step 1 exam


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Old 11-28-2009
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Question CD43 Versus CD34

CD43 and CD43 am so confused about them
Can anybody help me differentiate these so that I can answer the related USMLE question.

Thanks
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Old 11-29-2009
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CD43 also called Sialophorin is associated with Wiskott-Aldrich syndrome. http://www.ncbi.nlm.nih.gov/pubmed/2223062

CD34 also called Sialomucin is a cell surface marker that is present mainly in hematopoeitic stem cells in the bone marrow and aids in cell migration and cell-cell adhesion.
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Old 11-01-2011
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Idea! CD-34 marker on hematopoetic proginator cells

Found in AML.
Also distinguish Kaposi’s sarcoma, dermatofibrosarcoma protuberans/DSFP (both CD34+) from dermatofibroma (CD34-)
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Old 11-01-2011
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Smile CD-43,is a Pan T-Cell Marker

Also called leukosialin, sialophorin.
Has defective expression in T cells of males with Wiskott-Aldrich syndrome
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Old 04-11-2012
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Is this high yield? I haven't come across this before.
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Old 04-12-2012
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Default CD markers r high yield

Quote:
Originally Posted by Hope2Pass View Post
Is this high yield? I haven't come across this before.
yes they do ask questions about CD markers and these questions are almost always straight, to the point, short stem questions. in my step 1 exam i got three questions regarding CD markers of whch two i knew , and the third one i had never heard of
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