A 35-year-old male presents to his primary care doctor with complaints of headache and malaise. His blood pressure is elevated. He has periorbital and pretibial edema. Urinalysis reveals heavy proteinuria. Which of the following is the most likely principal component of his proteinuria?
(A) Albumin (B) Kappa light chains (C) Lambda light chains (D) Tamm-Horsfall protein (E) Transthyretin
Albumin I think. The light chains would be found in a urine sample in multiple myeloma in which a patient may present with back pain, malaise, and show monoclonal IgG spike. I don't know about T-H protein or transthyretin, however.
You can't detect imunoglobulin chains (light or heavy) with a simple urinalysis and like someone said you'd need more data to rule out the other two. Albuminuria is detactable by simple urinalysis.
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