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USMLE Step 1 Mnemonics Mnemonics, acronyms, reminders, and memorizing tips for the USMLE Step 1.


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Old 08-06-2009
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RBC Hemoglobin Dissociation Curve

Ever confused what cause a right shift and what cause a left shift?

Here's a quick mnemonic

Just remember that a right shift is DATE with CO2

CO2 --- that's obvious
D ---- 2,3 Diphosphoglycerate DPG
A ---- Acidosis
T ---- Temperature
E ---- Exercise


Any increase (not decrease) in these will shift to the right

Needless to say that everything else will shift the curve to the left such as HbF, Carbon monoxide, decreased DPG as in stored blood, alkalosis, decreased PCO2, hypothermia, and high altitude.

Hope that's useful

Last edited by Sabio; 07-26-2010 at 08:24 AM. Reason: Correction
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Old 08-16-2009
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in High altitude the shift to the left is initial
then the curve shift to the right
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Old 08-28-2009
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There's even an easier way to remember the right shifted curve

Which is by remembering the exercising muscle

In the exercising muscle you have
  • Acidosis, because of the lactic acid production
  • Increased CO2, obviously because of increased metabolism
  • Increased temperature, also because of increased metabolism
  • Increased 2,3 DPG because of increased glycolysis



Note: got this from Kaplan qbank
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Old 07-26-2010
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Quote:
Originally Posted by Sabio View Post
Ever confused what cause a right shift and what cause a left shift?

Here's a quick mnemonic

Just remember that a right shift is TAMED with CO2

CO2 --- that's obvious
T ---- Temperature
A ---- Acidosis
M ---- Methemoglobin
E ---- Exercise
D ---- 2,3 Diphosphoglycerate DPG

Methemoglobin left shifts the oxygen dissociation curve, plz correct the first post...
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Old 07-26-2010
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Quote:
Originally Posted by doc_study View Post
Methemoglobin left shifts the oxygen dissociation curve, plz correct the first post...
Thank you very much for your suggestion and feedback.
Yes, you are right. The post was wrong, I corrected it
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