Nikolsky's Sign Differential Diagnosis - USMLE Forums
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USMLE Step 2 CK Buzzwords Buzzwords that should ring a bell in USMLE Step 2 CK exam.

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Old 03-21-2010
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Skin Nikolsky's Sign Differential Diagnosis

Nikolsky's sign is a buzzword that should lead us to think of a number of skin conditions. However, frequently, the USMLE question maker will not often tell you the name out-rightly instead they usually describe it. Common descriptions include one of the two followings:
Rubbing the skin leads to sloughing of skin.
Lateral traction of the surrounding skin leads to sloughing (desquamation).

Now what causes that we should be thinking of?
  • Staphylococcal Scalded Skin Syndrome
  • Toxic Epidermal Necrolysis
  • Bullous impetigo
  • Pemphigus vulgaris (but not bullous pemphigoid) Read more
  • Epidermolysis bullosa
  • Second degree and Third degree burns
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Old 05-17-2010
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Old 02-28-2011
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Default completion

Also Stevens-Johnson syndrome (TEN applying to mucus membranes)
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Clinical-Signs, Dermatology-

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